Gene: PRKD2
Official Full Name: protein kinase D2provided by HGNC
Gene Summary: The protein encoded by this gene belongs to the protein kinase D (PKD) family of serine/threonine protein kinases. This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells. It can bind to diacylglycerol (DAG) in the trans-Golgi network (TGN) and may regulate basolateral membrane protein exit from TGN. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO08759 | PRKD2 Knockout cell line (HeLa) | Human | PRKD2 | 1:3~1:6 | Negative | Online Inquiry |
KO08760 | PRKD2 Knockout cell line (HCT 116) | Human | PRKD2 | 1:2~1:4 | Negative | Online Inquiry |
KO08761 | PRKD2 Knockout cell line (HEK293) | Human | PRKD2 | 1:3~1:6 | Negative | Online Inquiry |
KO08762 | PRKD2 Knockout cell line (A549) | Human | PRKD2 | 1:3~1:4 | Negative | Online Inquiry |
PRKD2 Gene Knockout Cell Lines are specialized cellular models engineered to eliminate the expression of the PRKD2 gene, which encodes for the protein kinase D2 involved in multiple signaling pathways related to cell function and proliferation. These knockout cell lines serve as vital tools for researchers investigating the biological roles of PRKD2 in various cellular processes such as apoptosis, migration, and cellular response to growth factors.
The mechanism underlying the utility of PRKD2 Gene Knockout Cell Lines lies in their ability to provide insight into the pathways influenced by PRKD2. Researchers can analyze the phenotypic and genotypic differences between knockout cells and their wild-type counterparts, facilitating the dissection of PRKD2's specific contributions to cellular behavior. This functionality is paramount in a wide range of research fields, including cancer biology, developmental biology, and neurobiology, where understanding the precise role of PRKD2 can elucidate disease mechanisms and potential therapeutic targets.
One of the primary advantages of using PRKD2 Gene Knockout Cell Lines is the specificity and reliability they offer. Unlike pharmacological inhibitors or RNA interference (RNAi), these cell lines provide a stable and reproducible system for long-term experiments, eliminating off-target effects commonly associated with other methods. This precision enables more accurate assessments of PRKD2's role in various biological processes, giving researchers confidence in their experimental outcomes.
Researchers and clinicians will find PRKD2 Gene Knockout Cell Lines valuable for both exploratory and confirmatory studies. By using these models, users can better understand PRKD2's implications in disease pathology and therapeutic resistance, paving the way for innovative strategies to combat various health conditions.
Our company specializes in providing cutting-edge tools for advanced biological research, and PRKD2 Gene Knockout Cell Lines exemplify our commitment to empowering scientists with high-quality products that enhance their investigative capabilities and contribute to breakthroughs in medical science.
Please note that all services are for research use only. Not intended for any clinical use.
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