Home / PPP6R2 Knockout Cell Lines

PPP6R2 Knockout Cell Lines

Gene: PPP6R2

Official Full Name: protein phosphatase 6 regulatory subunit 2provided by HGNC

Gene Summary: The protein encoded by this gene is a regulatory protein for the protein phosphatase-6 catalytic subunit. Together, these proteins act as a significant T-loop phosphatase for Aurora A, an essential mitotic kinase. Loss of function of either the regulatory or catalytic subunit of protein phosphatase-6 interferes with spindle formation and chromosome alignment. [provided by RefSeq, May 2017]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO32900 PPP6R2 Knockout cell line (HeLa) Human PPP6R2 1:3~1:6 Negative Online Inquiry
KO32901 PPP6R2 Knockout cell line (HCT 116) Human PPP6R2 1:2~1:4 Negative Online Inquiry
KO32902 PPP6R2 Knockout cell line (HEK293) Human PPP6R2 1:3~1:6 Negative Online Inquiry
KO32903 PPP6R2 Knockout cell line (A549) Human PPP6R2 1:3~1:4 Negative Online Inquiry

Background

PPP6R2 Gene Knockout Cell Lines are specialized cellular models designed to facilitate the study of the PPP6R2 gene, a critical component involved in cellular signaling and oncogenesis. These knockout cell lines are engineered using CRISPR/Cas9 technology, leading to the specific deletion of the PPP6R2 gene, which allows for an in-depth investigation into its role in various biological processes, particularly in tumor development and progression.

The primary function of PPP6R2 lies in its regulation of various signaling pathways, such as those associated with cell proliferation and apoptosis. By utilizing these knockout cell lines, researchers can elucidate the gene's contribution to cellular mechanisms, revealing insights into its implications in cancer biology as well as other diseases related to dysregulated signaling pathways. This makes the PPP6R2 knockout lines invaluable in both basic research and more applied clinical settings, where understanding the genetic drivers of disease is crucial for developing targeted therapies.

One of the key advantages of using PPP6R2 gene knockout cell lines over traditional methods is the precision of gene editing that allows for a complete and permanent loss of function. This level of specificity minimizes off-target effects, providing more reliable data on the gene’s role. Additionally, the availability of these cell lines streamlines experimental workflows and reduces the time and resource investment typically required for creating custom knockout models.

For researchers and clinicians, the ability to study the PPP6R2 gene in a controlled environment presents a unique opportunity to explore therapeutic targets and devise innovative treatment strategies. The profound insights gained from these cell lines can contribute significantly to the understanding of cancer mechanisms, enhancing the potential for novel interventions.

Our company prides itself on a commitment to advancing biological research through high-quality products and cutting-edge technologies, ensuring that researchers have access to the necessary tools to push the boundaries of their investigations. With expertise in genetic engineering and a focus on delivering reliable cellular models, we stand at the forefront of scientific innovation, providing products that truly meet the needs of the research community.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.