Gene: PPCDC
Official Full Name: phosphopantothenoylcysteine decarboxylaseprovided by HGNC
Gene Summary: Biosynthesis of coenzyme A (CoA) from pantothenic acid (vitamin B5) is an essential universal pathway in prokaryotes and eukaryotes. PPCDC (EC 4.1.1.36), one of the last enzymes in this pathway, converts phosphopantothenoylcysteine to 4-prime-phosphopantetheine (Daugherty et al., 2002 [PubMed 11923312]).[supplied by OMIM, Mar 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO14958 | PPCDC Knockout cell line (HeLa) | Human | PPCDC | 1:3~1:6 | Negative | Online Inquiry |
KO14959 | PPCDC Knockout cell line (HCT 116) | Human | PPCDC | 1:2~1:4 | Negative | Online Inquiry |
KO14960 | PPCDC Knockout cell line (HEK293) | Human | PPCDC | 1:3~1:6 | Negative | Online Inquiry |
KO14961 | PPCDC Knockout cell line (A549) | Human | PPCDC | 1:3~1:4 | Negative | Online Inquiry |
PPCDC Gene Knockout Cell Lines are specialized cellular models developed to facilitate the study of the phosphopantothenoylcysteine decarboxylase (PPCDC) gene, a critical player in coenzyme A biosynthesis. These cell lines are deliberately designed with targeted deletions of the PPCDC gene, allowing researchers to systematically investigate the gene's role in metabolic pathways and its implications in various physiological and pathological conditions.
The key function of these knockout cell lines lies in their ability to provide insights into the biochemical mechanisms governed by PPCDC. By observing cellular behavior in the absence of this enzyme, researchers can elucidate PPCDC's regulatory functions and its impact on cellular metabolism, including fatty acid synthesis and energy production. The use of these cell lines enables detailed analyses of metabolic disruptions linked to diseases such as obesity, diabetes, and cancer, fostering a deeper understanding of therapeutic targets.
From a scientific perspective, PPCDC Gene Knockout Cell Lines are essential in both basic research and translational studies. They offer a means to explore gene function in controlled environments, thus enhancing the development of gene therapy and drug discovery approaches. The unique advantage of utilizing these cell lines is the precision of genetic modification, which is essential for experiments that demand rigor and reproducibility.
Compared to alternative models, such as traditional knockdown systems or non-targeted mutations, PPCDC Gene Knockout Cell Lines offer unparalleled specificity. This specificity translates into more reliable data, minimizing confounding factors and enabling clearer interpretations of experimental outcomes. Moreover, these cell lines can be readily used in high-throughput screening platforms, making them indispensable for researchers focused on identifying novel pharmacological agents.
Researchers and clinicians interested in metabolic disorders or genetic research will find tremendous value in PPCDC Gene Knockout Cell Lines. Their ability to mimic in vivo conditions offers a robust platform for studying disease mechanisms and testing potential therapeutic interventions.
With a deep commitment to advancing biological research, our company specializes in developing high-quality, precisely engineered biological products, positioning us at the forefront of innovative scientific solutions. We strive to equip the research community with tools that empower discoveries and foster advancements in health and medicine.
Please note that all services are for research use only. Not intended for any clinical use.
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