Gene: PLPPR2
Official Full Name: phospholipid phosphatase related 2provided by HGNC
Gene Summary: Predicted to enable phosphatidate phosphatase activity. Predicted to be involved in phospholipid dephosphorylation; phospholipid metabolic process; and signal transduction. Predicted to be located in membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO15027 | PLPPR2 Knockout cell line (HeLa) | Human | PLPPR2 | 1:3~1:6 | Negative | Online Inquiry |
KO15028 | PLPPR2 Knockout cell line (HCT 116) | Human | PLPPR2 | 1:2~1:4 | Negative | Online Inquiry |
KO15029 | PLPPR2 Knockout cell line (HEK293) | Human | PLPPR2 | 1:3~1:6 | Negative | Online Inquiry |
KO15030 | PLPPR2 Knockout cell line (A549) | Human | PLPPR2 | 1:3~1:4 | Negative | Online Inquiry |
PLPPR2 Gene Knockout Cell Lines are genetically engineered cellular models specifically designed to investigate the physiological role of the PLPPR2 gene, which is known to be involved in myelin sheath formation and maintenance. By employing CRISPR-Cas9 technology, these cell lines achieve a complete knockout of PLPPR2, allowing researchers to elucidate its biological functions through observation of genes and pathways altered in its absence.
The key function of the PLPPR2 Gene Knockout Cell Lines is to provide a controlled environment where researchers can systematically dissect the impact of PLPPR2 deficiency on cellular behavior, particularly in oligodendrocytes and neurons. These cell lines enable the study of various mechanisms, such as signal transduction pathways and cellular differentiation processes, which are critical for understanding diseases related to myelin defects, including multiple sclerosis and leukodystrophies.
In scientific research and clinical settings, the importance of these cell lines lies in their ability to facilitate high-throughput screening of potential therapeutic agents, helping identify new targets for drug development aimed at demyelinating diseases. By utilizing PLPPR2 knockout models, researchers can gain deeper insights into the pathophysiology of neurodegenerative disorders, thereby contributing to advancements in both fundamental biology and translational medicine.
What sets PLPPR2 Gene Knockout Cell Lines apart from alternatives is their precision and reliability. Unlike traditional knockdown approaches, which can result in incomplete gene silencing and variable phenotypes, our knockout models ensure a complete disruption of gene function, providing consistent and reproducible results. Furthermore, they are compatible with a variety of cellular assays, enhancing their utility in a wide range of experimental setups.
For researchers and clinicians seeking innovative solutions to advance their work on myelin-related conditions, PLPPR2 Gene Knockout Cell Lines offer tremendous value in terms of research depth, access to novel insights, and the potential to pave the way for new therapeutic interventions. Our company, with its commitment to pioneering biomedical research tools, provides these cutting-edge cell lines, reflecting decades of expertise in genetic engineering and cell biology, aimed at empowering your research endeavors.
Please note that all services are for research use only. Not intended for any clinical use.
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