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PLEKHH2 Knockout Cell Lines

Gene: PLEKHH2

Official Full Name: pleckstrin homology, MyTH4 and FERM domain containing H2provided by HGNC

Gene Summary: Predicted to enable actin binding activity. Predicted to be involved in negative regulation of actin filament depolymerization. Located in several cellular components, including cytosol; lamellipodium; and nuclear body. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO26636 PLEKHH2 Knockout cell line (HeLa) Human PLEKHH2 1:3~1:6 Negative Online Inquiry
KO26637 PLEKHH2 Knockout cell line (HCT 116) Human PLEKHH2 1:2~1:4 Negative Online Inquiry
KO26638 PLEKHH2 Knockout cell line (HEK293) Human PLEKHH2 1:3~1:6 Negative Online Inquiry
KO26639 PLEKHH2 Knockout cell line (A549) Human PLEKHH2 1:3~1:4 Negative Online Inquiry

Background

PLEKHH2 Gene Knockout Cell Lines are engineered cellular models utilized for investigating the functional role of the PLEKHH2 gene. This gene encodes a protein that has been implicated in various cellular processes, including vesicular trafficking and cytoskeletal organization. The knockout approach involves the precise deletion of the PLEKHH2 gene, enabling researchers to elucidate the gene's contribution to cellular behavior and its potential implications in diseases such as cancer and neurodegeneration.

The key functions of these knockout cell lines allow for a deeper understanding of the PLEKHH2 protein's mechanistic pathways. By providing a system where the gene's activity has been abolished, researchers can assess alterations in cellular morphology, proliferation, and signaling pathways. This is vital for delineating the gene's physiological roles and its interactions within the cellular environment.

In research and clinical settings, PLEKHH2 Gene Knockout Cell Lines serve as powerful tools for drug discovery, target validation, and biomarker identification. They enable scientists to study disease mechanisms and develop therapeutic strategies more effectively, providing a clear pathway to translational research and potential clinical applications.

What sets our PLEKHH2 Gene Knockout Cell Lines apart from alternatives is the precision and reliability of our gene editing technology. Sourced from rigorously validated methodologies, these cell lines come with comprehensive documentation, including gene validation and characterization data, ensuring reproducibility and trustworthiness.

For researchers and clinicians, the implications of utilizing PLEKHH2 knockout lines are significant. They enhance experimental reliability and data quality, allowing for insights that could lead to innovative therapies and treatments in a timely manner. The value of this product lies in its ability to streamline research processes and accelerate discoveries.

Our company boasts extensive expertise in the field of genetic engineering and cell line development, offering a robust portfolio of genetically modified cell models. We are committed to supporting the scientific community with high-quality biological products that advance research and improve clinical outcomes.

Please note that all services are for research use only. Not intended for any clinical use.

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