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PLEKHD1 Knockout Cell Lines

Gene: PLEKHD1

Official Full Name: pleckstrin homology and coiled-coil domain containing D1provided by HGNC

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO21441 PLEKHD1 Knockout cell line (HCT 116) Human PLEKHD1 1:2~1:4 Negative Online Inquiry

Background

PLEKHD1 Gene Knockout Cell Lines are specialized cellular models created through targeted gene knockout techniques to study the functional implications of the PLEKHD1 gene, which encodes a protein suggested to be involved in cytoskeletal dynamics and cellular signaling. These cell lines facilitate the in-depth analysis of gene function and protein interactions by allowing researchers to observe the phenotypic consequences of PLEKHD1 loss, which can have profound implications in understanding various diseases, including cancers and neurodegenerative disorders.

The key function of these knockout cell lines lies in their ability to accurately mimic the absence of PLEKHD1, providing a platform for examining not only the loss of specific cellular functions but also the regulatory mechanisms associated with these changes. By utilizing CRISPR-Cas9 technology or other gene editing tools, these cell lines provide an effective way to study gene function, helping elucidate cellular pathways and interactions that are critical in health and disease contexts.

From a scientific perspective, PLEKHD1 Gene Knockout Cell Lines are invaluable for research and clinical applications, particularly in drug discovery and mechanistic studies. They allow for the screening of therapeutic compounds targeting the pathways influenced by PLEKHD1 and can be used to understand disease mechanisms at a molecular level. Given the central role of the PLEKHD1 gene in cellular response mechanisms, the insights gained from these models can significantly contribute to advancements in targeted therapies.

Compared to traditional cell lines, these knockout models provide a more precise tool for researchers looking to dissect the functional roles of genes in specific pathways. They eliminate the confounding factors associated with partial knockdowns or overexpression systems, thus offering clearer interpretations of experimental data. Additionally, the customization potential of these cell lines enables researchers to tailor experiments to their specific needs, increasing experimental rigor and relevance.

For researchers, clinicians, and pharmaceutical developers, PLEKHD1 Gene Knockout Cell Lines represent not just a product but a crucial resource for enhancing our understanding of gene function and advancing therapeutic strategies. With a commitment to excellence in gene editing technologies and a focus on supporting cutting-edge research, our company stands at the forefront of delivering high-quality biological research tools that empower the scientific community.

Please note that all services are for research use only. Not intended for any clinical use.

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