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PLEKHB1 Knockout Cell Lines

Gene: PLEKHB1

Official Full Name: pleckstrin homology domain containing B1provided by HGNC

Gene Summary: Predicted to enable protein homodimerization activity. Predicted to be involved in regulation of cell differentiation. Located in membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO15074 PLEKHB1 Knockout cell line (HeLa) Human PLEKHB1 1:3~1:6 Negative Online Inquiry
KO15075 PLEKHB1 Knockout cell line (HCT 116) Human PLEKHB1 1:2~1:4 Negative Online Inquiry
KO15076 PLEKHB1 Knockout cell line (HEK293) Human PLEKHB1 1:3~1:6 Negative Online Inquiry

Background

PLEKHB1 Gene Knockout Cell Lines are specifically engineered cellular models that facilitate the study of the PLEKHB1 gene function, which is implicated in various biological processes, including cell proliferation and apoptosis. These cell lines have undergone precise genome editing using CRISPR/Cas9 technology, resulting in a complete disruption of the PLEKHB1 gene. This alteration provides researchers with robust tools to investigate the molecular pathways influenced by PLEKHB1, allowing for detailed analyses of gene function and its role in health and disease.

The key mechanism behind PLEKHB1 Gene Knockout Cell Lines lies in the targeted gene-editing capabilities that allow for specific knockout of the PLEKHB1 gene. This process not only preserves the overall cellular environment but also mimics conditions seen in various pathophysiological states. Consequently, these cell lines serve as an invaluable asset for elucidating the gene's contributions to pathways associated with cancer, neurological disorders, and immune responses.

In research and clinical settings, these knockout cell lines offer significant advantages for drug discovery and therapeutic development. They enable scientists to conduct functional studies that can lead to insights into potential drug targets and biomarkers for disease progression. Compared to conventional models, PLEKHB1 Gene Knockout Cell Lines provide a more accurate and reliable reflection of human biological processes, thereby enhancing the validity of experimental results.

Researchers and clinicians can greatly benefit from the use of these cell lines, as they streamline experimental workflows and improve the reproducibility of findings. By employing such advanced models, labs can accelerate their research and development efforts, ultimately leading to innovations in treatment strategies.

Our company specializes in providing high-quality gene-editing services and products, ensuring that researchers have access to the most effective tools for their scientific inquiries. With our expertise in genetic engineering and commitment to advancing biological research, we are dedicated to supporting the scientific community in unlocking the complexities of gene functions and mechanisms.

Please note that all services are for research use only. Not intended for any clinical use.

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