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PHF2 Knockout Cell Lines

Gene: PHF2

Official Full Name: PHD finger protein 2provided by HGNC

Gene Summary: This gene encodes a protein which contains a zinc finger-like PHD (plant homeodomain) finger, distinct from other classes of zinc finger motifs, and a hydrophobic and highly conserved domain. The PHD finger shows the typical Cys4-His-Cys3 arrangement. PHD finger genes are thought to belong to a diverse group of transcriptional regulators possibly affecting eukaryotic gene expression by influencing chromatin structure. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO06613 PHF2 Knockout cell line (HeLa) Human PHF2 1:3~1:6 Negative Online Inquiry
KO06614 PHF2 Knockout cell line (HCT 116) Human PHF2 1:2~1:4 Negative Online Inquiry
KO06615 PHF2 Knockout cell line (HEK293) Human PHF2 1:3~1:6 Negative Online Inquiry
KO06616 PHF2 Knockout cell line (A549) Human PHF2 1:3~1:4 Negative Online Inquiry

Background

PHF2 Gene Knockout Cell Lines are genetically engineered cell lines created to specifically disrupt the PHF2 gene, which encodes a protein known to play a critical role in epigenetic regulation and cellular response to stress. These cell lines facilitate the investigation of the physiological and pathological roles of the PHF2 protein, thereby providing researchers with a vital tool for understanding various cellular mechanisms. By employing CRISPR-Cas9 technology during the knockout process, the precise editing of the genomic sequence enhances the reliability of results in subsequent assays.

The primary function of PHF2 Gene Knockout Cell Lines lies in their ability to investigate the gene’s involvement in cellular processes such as proliferation, differentiation, and apoptosis. Additionally, these cell lines serve as an indispensable resource for studying the impact of PHF2 on gene expression regulation and the response to external stimuli. By enabling specific investigations into these pathways, researchers can uncover the underlying molecular mechanisms that contribute to diseases, such as various cancers and neurodegenerative disorders.

The scientific importance of PHF2 Gene Knockout Cell Lines is underscored by their applications in both basic and translational research. These cell lines can be utilized in drug discovery, allowing scientists to screen for novel therapeutics that target pathways influenced by PHF2. Furthermore, they hold potential for clinical applications, such as developing personalized medicine strategies based on the regulatory roles of PHF2 in individual patient tumors.

What sets PHF2 Gene Knockout Cell Lines apart from alternative models is their high specificity, reproducibility, and ease of use, which result from advanced genetic engineering techniques. Researchers benefit from access to a consistent and reliable platform that rapidly accelerates the discovery process.

This product is of substantial value to researchers and clinicians who seek to elucidate biological pathways, identify potential drug targets, and advance personalized medicine approaches. With a robust understanding of gene function and expertise in gene editing technologies, our company is dedicated to providing high-quality biological products, including the PHF2 Gene Knockout Cell Lines, to enhance your research endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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