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PCED1A Knockout Cell Lines

Gene: PCED1A

Official Full Name: PC-esterase domain containing 1Aprovided by HGNC

Gene Summary: The protein encoded by this gene is a member of the GDSL/SGNH superfamily. Members of this family are hydrolytic enzymes with esterase and lipase activity and broad substrate specificity. This protein belongs to the Pmr5-Cas1p-esterase subfamily in that it contains the catalytic triad comprised of serine, aspartate and histidine and lacks two conserved regions (glycine after strand S2 and GxND motif). A pseudogene of this gene has been identified on the long arm of chromosome 2. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Sep 2012]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO15300 PCED1A Knockout cell line (HeLa) Human PCED1A 1:3~1:6 Negative Online Inquiry
KO15301 PCED1A Knockout cell line (HCT 116) Human PCED1A 1:2~1:4 Negative Online Inquiry
KO15302 PCED1A Knockout cell line (HEK293) Human PCED1A 1:3~1:6 Negative Online Inquiry
KO15303 PCED1A Knockout cell line (A549) Human PCED1A 1:3~1:4 Negative Online Inquiry

Background

PCED1A Gene Knockout Cell Lines are engineered cell models designed to facilitate the study of the PCED1A gene, which encodes a protein implicated in various cellular processes, including cell proliferation and differentiation. By utilizing CRISPR-Cas9 technology, these cell lines have been precisely modified to eliminate the expression of the PCED1A gene, enabling researchers to investigate the gene’s functions and its role in pathophysiological conditions.

The primary function of PCED1A Gene Knockout Cell Lines is to serve as a valuable tool in elucidating the molecular pathways influenced by the PCED1A gene. These knockout models provide insights into how the absence of the gene affects cellular behavior, potentially uncovering novel mechanisms associated with diseases such as cancer and metabolic disorders. By examining phenotypic changes, researchers can assess cellular responses to various stimuli, thus offering an avenue for drug discovery and therapeutic development.

The scientific importance of these knockout cell lines extends to both basic research and clinical applications, as they enable the identification of gene function and interaction, which are critical for advancing our understanding of gene-related diseases. Moreover, the precision of the CRISPR-Cas9 approach ensures reproducibility and reliability in experimental outcomes, making it a preferred choice among researchers.

Compared to traditional gene knockdown methods, such as RNA interference, PCED1A Gene Knockout Cell Lines provide a more permanent and complete loss of gene function, allowing for the exploration of long-term effects without confounding results from transient gene modulation. This permanent knockout significantly enhances the reliability of experimental data.

For researchers and clinicians, the value of PCED1A Gene Knockout Cell Lines lies in their ability to foster innovative research that could lead to breakthroughs in genetic therapies and biomarker identification. The provision of robust and well-characterized cell lines aids in accelerating the pace of discovery, making these products indispensable for scientists aiming to deepen their understanding of gene function.

Our company prides itself on its expertise in developing high-quality genetic tools and model systems. We are committed to supporting the scientific community with advanced solutions that enhance research capabilities and facilitate the exploration of complex biological queries.

Please note that all services are for research use only. Not intended for any clinical use.

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