Gene: PCDH10
Official Full Name: protocadherin 10provided by HGNC
Gene Summary: This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. This family member contains 6 extracellular cadherin domains, a transmembrane domain and a cytoplasmic tail differing from those of the classical cadherins. The encoded protein is a cadherin-related neuronal receptor thought to function in the establishment of specific cell-cell connections in the brain. This gene plays a role in inhibiting cancer cell motility and cell migration. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2015]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO15313 | PCDH10 Knockout cell line (HEK293) | Human | PCDH10 | 1:3~1:6 | Negative | Online Inquiry |
PCDH10 Gene Knockout Cell Lines are specialized cellular models engineered to effectively silence the expression of the PCDH10 gene, which encodes the protocadherin-10 protein involved in processes such as cell adhesion and signal transduction. By employing CRISPR-Cas9 technology, these knockout cell lines exhibit profound alterations in molecular pathways, allowing researchers to investigate the gene's role in various biological contexts, including neuronal differentiation, tumorigenesis, and synaptic function.
The primary function of these cell lines lies in their ability to facilitate in-depth studies of PCDH10’s contributions to cellular behaviors and interactions. The knockout of this gene can reveal insights into how its absence manifests in cellular communication deficits, proliferative changes, or modified response to external stimuli. This makes the PCDH10 knockout cell lines invaluable in expanding our understanding of diseases, particularly those related to neurological disorders and cancer.
In scientific research and clinical applications, these cell lines serve as essential tools for genetic studies, drug screening, and developing targeted therapies. Their ability to mimic specific disease states provides a robust platform for elucidating pathological mechanisms and for preclinical testing of novel treatment strategies.
Compared to conventional cell lines, the PCDH10 Gene Knockout Cell Lines offer significant advantages by providing a more authentic representation of PCDH10-related processes in vivo. While typical models may offer a partial view of biological functions, these knockout lines allow for clearer interpretation of the loss-of-function effects, enabling researchers to derive more impactful conclusions.
For researchers and clinicians dedicated to understanding the complex interplay of gene expression and phenotypic outcomes, leveraging PCDH10 Gene Knockout Cell Lines is not only valuable but essential for advancing knowledge in the field. These insights can directly support the development of innovative therapies that target underlying causes of disease rather than just symptoms.
Our company is committed to providing high-quality, reliable biological products and has extensive expertise in gene editing technologies. We ensure that our PCDH10 Gene Knockout Cell Lines meet rigorous standards for genetic integrity and cell line authenticity, empowering scientists in their quest for discovery.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.