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PATL1 Knockout Cell Lines

Gene: PATL1

Official Full Name: PAT1 homolog 1, processing body mRNA decay factorprovided by HGNC

Gene Summary: Enables poly(G) binding activity and poly(U) RNA binding activity. Involved in P-body assembly and deadenylation-dependent decapping of nuclear-transcribed mRNA. Located in CCR4-NOT complex; P-body; and cytosol. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO28190 PATL1 Knockout cell line (HeLa) Human PATL1 1:3~1:6 Negative Online Inquiry
KO28191 PATL1 Knockout cell line (HCT 116) Human PATL1 1:2~1:4 Negative Online Inquiry
KO28192 PATL1 Knockout cell line (HEK293) Human PATL1 1:3~1:6 Negative Online Inquiry
KO28193 PATL1 Knockout cell line (A549) Human PATL1 1:3~1:4 Negative Online Inquiry

Background

PATL1 Gene Knockout Cell Lines are genetically engineered models that specifically lack the expression of the PATL1 gene, a crucial player in various cellular processes, including mRNA metabolism and translation regulation. These cell lines have been meticulously developed using CRISPR/Cas9 technology, enabling precise gene editing. The elimination of PATL1 allows researchers to investigate its role in cellular function and disease mechanisms, particularly in relation to processes such as cell division, differentiation, and responses to stress.

The primary functions of PATL1 include its involvement in translational repression and mRNA localization, which are vital for maintaining cellular homeostasis. By studying PATL1 knockout cell lines, scientists can better understand the consequences of disrupted gene function, paving the way for significant insights into diseases such as cancer, neurodegenerative disorders, and metabolic syndromes. The knockout cell lines provide a unique platform for studying the dynamic interactions between PATL1 and other molecular players in the cell, fostering high-impact research projects.

In comparison to traditional cell line models, PATL1 knockout cells offer a targeted and effective way to dissect the specific roles of the PATL1 gene without resorting to global gene knockdown techniques. This specificity enhances data reliability and reproducibility, making these cell lines a valuable resource for both academic and commercial research laboratories.

The value of PATL1 Gene Knockout Cell Lines lies in their ability to accelerate scientific discovery, enabling researchers to elucidate gene function and its implications in human health. With these tools, users are empowered to conduct functional assays, drug testing, and genetic screening with greater precision.

As a leader in genetic engineering and cell line development, our company prides itself on providing high-quality biological products that facilitate advanced research in genetics and molecular biology. Our expertise ensures that researchers and clinicians have access to the most reliable models for their studies, driving innovation and breakthroughs in scientific understanding.

Please note that all services are for research use only. Not intended for any clinical use.

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