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PARD6G Knockout Cell Lines

Gene: PARD6G

Official Full Name: par-6 family cell polarity regulator gammaprovided by HGNC

Gene Summary: Predicted to be involved in centrosome cycle; establishment or maintenance of epithelial cell apical/basal polarity; and regulation of cellular localization. Predicted to be located in cytosol and plasma membrane. Predicted to be part of PAR polarity complex. Predicted to be active in apical plasma membrane; cell cortex; and nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO08661 PARD6G Knockout cell line (HeLa) Human PARD6G 1:3~1:6 Negative Online Inquiry
KO08662 PARD6G Knockout cell line (HCT 116) Human PARD6G 1:2~1:4 Negative Online Inquiry
KO08663 PARD6G Knockout cell line (HEK293) Human PARD6G 1:3~1:6 Negative Online Inquiry
KO08664 PARD6G Knockout cell line (A549) Human PARD6G 1:3~1:4 Negative Online Inquiry

Background

PARD6G Gene Knockout Cell Lines are genetically engineered cellular models designed to study the function of the PARD6G gene, a key regulator involved in various cellular processes, including polarity and signal transduction. These cell lines have been meticulously developed using CRISPR-Cas9 technology to introduce targeted gene deletions, thereby providing a powerful tool for researchers aiming to elucidate the role of PARD6G in both normal physiology and pathological conditions.

The primary mechanism of action of these knockout cell lines involves the complete interruption of the PARD6G coding sequence, which subsequently affects downstream signaling pathways crucial for cellular organization. By eliminating this gene, researchers can investigate the consequences on cell behavior, including migration, proliferation, and differentiation, facilitating deeper insights into cancer biology or developmental processes.

In terms of scientific importance, PARD6G Gene Knockout Cell Lines have a vital role in the research landscape, particularly in the fields of cancer research, immunology, and developmental biology. Given that PARD6G is implicated in several signaling cascades, these cell lines can serve as a platform for investigating drug responses, therapeutic targets, and the mechanisms of disease.

What sets these knockout lines apart from alternative models is their robustness and reliability. The CRISPR-mediated knockout ensures high specificity and efficiency, reducing off-target effects often associated with other gene-editing techniques. Additionally, these cell lines are validated for consistent performance across various experiments, providing confidence in reproducibility and data integrity.

For researchers and clinicians, the PARD6G Gene Knockout Cell Lines present a unique opportunity to explore novel therapeutic strategies and functional genomics with precision. The availability of these models can significantly enhance the quality of research outcomes, leading to the discovery of potentially groundbreaking treatments.

Our company specializes in providing cutting-edge genetic tools and cell line models that drive innovation in biological research. With expertise in molecular biology and a strong commitment to quality, we equip researchers with the resources necessary to advance their studies and achieve their scientific objectives.

Please note that all services are for research use only. Not intended for any clinical use.

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