Gene: OXNAD1
Official Full Name: oxidoreductase NAD binding domain containing 1provided by HGNC
Gene Summary: Predicted to enable oxidoreductase activity. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO23267 | OXNAD1 Knockout cell line (HeLa) | Human | OXNAD1 | 1:3~1:6 | Negative | Online Inquiry |
KO23268 | OXNAD1 Knockout cell line (HCT 116) | Human | OXNAD1 | 1:2~1:4 | Negative | Online Inquiry |
KO23269 | OXNAD1 Knockout cell line (HEK293) | Human | OXNAD1 | 1:3~1:6 | Negative | Online Inquiry |
KO23270 | OXNAD1 Knockout cell line (A549) | Human | OXNAD1 | 1:3~1:4 | Negative | Online Inquiry |
OXNAD1 Gene Knockout Cell Lines are specialized cellular models engineered to elucidate the role of the OXNAD1 gene, which plays a crucial part in mitochondrial function and cellular energy metabolism. These cell lines have been meticulously developed using advanced CRISPR-Cas9 gene editing technology, enabling the precise knockout of the OXNAD1 gene. This loss of function serves as a powerful tool for researchers seeking to investigate the effects of OXNAD1 deficiency on cellular processes, including oxidative phosphorylation, reactive oxygen species (ROS) production, and metabolic regulation.
The primary mechanism of these knockout cell lines involves the targeted disruption of the OXNAD1 gene, leading to the absence of its protein product. This interruption can significantly alter metabolic pathways, providing insights into the gene's role in diseases related to mitochondrial dysfunction, such as metabolic syndromes and neurodegenerative disorders. Consequently, researchers can utilize these cell lines to evaluate the impact of OXNAD1 on cell viability, proliferation, and response to various pharmacological agents.
Scientifically, the OXNAD1 gene knockout cell lines hold substantial importance in both research and clinical applications. They facilitate the study of mitochondrial biogenesis and function, promoting a deeper understanding of energy metabolism's implications in disease pathology. Furthermore, these models can be invaluable in drug discovery, allowing for the assessment of therapeutic targets associated with mitochondrial dysfunction.
What sets our OXNAD1 Gene Knockout Cell Lines apart from alternatives is their verified genetics and reproducibility, coupled with comprehensive user guides and support for optimal experimental workflows. Researchers and clinicians can be confident in the reliability of our cell lines for generating consistent and interpretable results.
In summary, the OXNAD1 Gene Knockout Cell Lines represent a state-of-the-art resource for advancing our understanding of mitochondrial dynamics and their relevance in health and disease. Our company prides itself on its extensive expertise in biogenetics and dedication to providing high-quality biological products that empower scientific discovery and clinical advancement.
Please note that all services are for research use only. Not intended for any clinical use.
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