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OSCP1 Knockout Cell Lines

Gene: OSCP1

Official Full Name: organic solute carrier partner 1provided by HGNC

Gene Summary: Enables transmembrane transporter activity. Involved in xenobiotic detoxification by transmembrane export across the plasma membrane. Located in basal plasma membrane and cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO26861 OSCP1 Knockout cell line (HeLa) Human OSCP1 1:3~1:6 Negative Online Inquiry
KO26862 OSCP1 Knockout cell line (HCT 116) Human OSCP1 1:2~1:4 Negative Online Inquiry
KO26863 OSCP1 Knockout cell line (HEK293) Human OSCP1 1:3~1:6 Negative Online Inquiry
KO26864 OSCP1 Knockout cell line (A549) Human OSCP1 1:3~1:4 Negative Online Inquiry

Background

OSCP1 Gene Knockout Cell Lines represent a cutting-edge tool specifically engineered for the exploration and manipulation of the OSCP1 gene, which encodes the outer shelf of the mitochondrial ATP synthase complex. These cell lines are meticulously developed through CRISPR/Cas9 technology, allowing for the precise knockout of the OSCP1 gene. By elucidating the role of OSCP1 in mitochondrial function, researchers can gain invaluable insights into its involvement in energy metabolism, cell proliferation, and apoptosis.

The key function of OSCP1 Gene Knockout Cell Lines lies in their utility for studying the physiological and pathological implications of OSCP1 deficiency. The absence of the OSCP1 protein alters the assembly and activity of ATP synthase, providing a unique platform to investigate various metabolic pathways and their dysregulation in diseases such as cancer and neurodegenerative disorders. Mechanistically, this allows scientists to dissect the regulation of oxidative phosphorylation and its contribution to cellular bioenergetics.

The scientific importance of OSCP1 Gene Knockout Cell Lines extends into both research and clinical applications. They serve as a critical resource for drug discovery, enabling the identification of novel therapeutic targets and biochemical pathways associated with metabolic diseases. Additionally, these cell lines facilitate the validation of hypotheses regarding mitochondrial dysfunction, positioning researchers to better understand the molecular basis of several disease states.

What sets our OSCP1 Gene Knockout Cell Lines apart from alternative products is the rigor of our validation process, ensuring consistent and reproducible results. Our cell lines are derived from multiple backgrounds, allowing researchers the flexibility to choose conditions that best suit their experimental designs. The knockouts have been confirmed through genotyping and functional assays, providing confidence in the reliability of the system.

For researchers and clinicians focusing on mitochondrial biology or metabolic disease, the OSCP1 Gene Knockout Cell Lines offer an invaluable resource to refine their studies and propel their research forward. This innovative product represents our commitment to delivering high-quality biological tools, backed by years of expertise and a dedication to advancing scientific discovery. Our reputation in the field assures users that they are utilizing some of the most rigorously developed products available to support their groundbreaking work.

Please note that all services are for research use only. Not intended for any clinical use.

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