Gene: OR10AC1
Official Full Name: olfactory receptor family 10 subfamily AC member 1 (gene/pseudogene)provided by HGNC
Gene Summary: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. This olfactory receptor gene is a segregating pseudogene, where some individuals have an allele that encodes a functional olfactory receptor, while other individuals have an allele encoding a protein that is predicted to be non-functional. [provided by RefSeq, Jan 2017]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO15464 | OR10AC1 Knockout cell line (HeLa) | Human | OR10AC1 | 1:3~1:6 | Negative | Online Inquiry |
KO15465 | OR10AC1 Knockout cell line (HCT 116) | Human | OR10AC1 | 1:2~1:4 | Negative | Online Inquiry |
KO15466 | OR10AC1 Knockout cell line (HEK293) | Human | OR10AC1 | 1:3~1:6 | Negative | Online Inquiry |
KO15467 | OR10AC1 Knockout cell line (A549) | Human | OR10AC1 | 1:3~1:4 | Negative | Online Inquiry |
OR10AC1 Gene Knockout Cell Lines are engineered cellular models specifically designed to study the functional roles of the OR10AC1 gene, which has significant implications in olfactory receptor signaling pathways. By creating knockout variants, where the OR10AC1 gene is selectively disrupted, researchers can observe the resultant phenotypic changes and elucidate the gene's contributions to sensory perception and neurological functions. This functionality provides a unique avenue to investigate the underlying mechanisms of olfactory disorders and other related physiological processes.
The key function of these knockout cell lines lies in their ability to facilitate targeted research focused on gene behavior, signal transduction pathways, and the effects of loss-of-function mutations. With the absence of the OR10AC1 gene, scientists can analyze alterations in cellular responses, receptor interactions, and metabolic pathways that are critically influenced by olfactory signaling. This model stands as an invaluable tool for researchers exploring neurobiology, genetics, and pharmacology.
In terms of scientific importance, OR10AC1 Gene Knockout Cell Lines are poised to advance our understanding of not only basic biological mechanisms but also potential clinical applications, including drug development and gene therapy strategies targeted at olfactory conditions. They offer a way to screen compounds that may modulate or restore dysfunctional olfactory receptor activity, making them essential in translational research.
Compared to traditional wild-type cell lines, these knockout models provide a more precise approach for studying specific gene functions, elevating their relevance in modern genetic research. The specificity of OR10AC1 gene knockout enables researchers to avoid the complications arising from the compensatory mechanisms often present in intact pathways, ensuring clearer insights and more reliable experimental outcomes.
For researchers, clinicians, and pharmaceutical developers, the value of OR10AC1 Gene Knockout Cell Lines is underscored by their ability to yield significant results that inform our understanding of compound interactions and potential treatments. Our company prides itself on its extensive experience in developing innovative biological products that support the research community, ensuring that our offerings are not only scientifically sound but tailored for maximal impact in advancing human health and understanding.
Please note that all services are for research use only. Not intended for any clinical use.
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