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NLRX1 Knockout Cell Lines

Gene: NLRX1

Official Full Name: NLR family member X1provided by HGNC

Gene Summary: The protein encoded by this gene is a member of the NLR family and localizes to the outer mitochondrial membrane. The encoded protein is a regulator of mitochondrial antivirus responses. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Aug 2013]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO15707 NLRX1 Knockout cell line (HeLa) Human NLRX1 1:3~1:6 Negative Online Inquiry
KO15708 NLRX1 Knockout cell line (HCT 116) Human NLRX1 1:2~1:4 Negative Online Inquiry
KO15709 NLRX1 Knockout cell line (HEK293) Human NLRX1 1:3~1:6 Negative Online Inquiry
KO15710 NLRX1 Knockout cell line (A549) Human NLRX1 1:3~1:4 Negative Online Inquiry

Background

NLRX1 Gene Knockout Cell Lines represent a cutting-edge tool in cellular biology, specifically designed to facilitate the study of NLRX1, a gene implicated in various immune responses and cellular signaling pathways. These engineered cell lines are created using precise genome editing techniques, such as CRISPR/Cas9, to eliminate the NLRX1 gene, thereby enabling researchers to dissect its functional roles in both normal and pathological contexts.

The primary function of these knockout cell lines is to serve as an in vitro model that allows for the examination of NLRX1-deletion effects on cellular processes, particularly those related to inflammation and apoptosis. By observing the resultant phenotypes, scientists can elucidate the molecular mechanisms through which NLRX1 regulates immune signaling, potentially influencing the development of treatments for diseases like autoimmune disorders and cancers.

The scientific significance of NLRX1 Gene Knockout Cell Lines extends beyond basic research; they have vital applications in drug discovery and development, where understanding the targeted pathways can lead to novel therapeutics. Clinically, the insights garnered from experiments using these cell lines can inform patient-specific approaches in precision medicine, particularly in conditions where NLRX1 modulation may yield beneficial effects.

What sets our NLRX1 Gene Knockout Cell Lines apart from alternative products is their high specificity, validated performance characteristics, and the comprehensive support offered to customers. Our proprietary methodology ensures consistent reproducibility in experimental outcomes, which is essential for reliable data generation. Furthermore, these cell lines are optimized for various experimental conditions, making them adaptable for a wide range of research applications.

The value of NLRX1 Gene Knockout Cell Lines is most evident in their potential to advance our understanding of crucial cellular pathways and contribute significantly to innovative therapeutic strategies. Our company, with its strong foundation in molecular biology and genetic engineering, is committed to providing high-quality biological tools that empower researchers and clinicians in their pursuit of groundbreaking discoveries.

Please note that all services are for research use only. Not intended for any clinical use.

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