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NCBP3 Knockout Cell Lines

Gene: NCBP3

Official Full Name: nuclear cap binding subunit 3provided by HGNC

Gene Summary: Enables RNA 7-methylguanosine cap binding activity and mRNA binding activity. Involved in defense response to virus; mRNA export from nucleus; and snRNA export from nucleus. Located in cytoplasm and nuclear speck. Part of nuclear cap binding activity complex. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO15840 NCBP3 Knockout cell line (HeLa) Human NCBP3 1:3~1:6 Negative Online Inquiry
KO15841 NCBP3 Knockout cell line (HCT 116) Human NCBP3 1:2~1:4 Negative Online Inquiry
KO15842 NCBP3 Knockout cell line (HEK293) Human NCBP3 1:3~1:6 Negative Online Inquiry
KO15843 NCBP3 Knockout cell line (A549) Human NCBP3 1:3~1:4 Negative Online Inquiry

Background

NCBP3 Gene Knockout Cell Lines are highly specialized cellular models characterized by the intentional disruption of the NCBP3 gene, a critical component in mRNA processing and stability. These cell lines are engineered using advanced CRISPR-Cas9 technology, which allows for precise and efficient genome editing. As a result, researchers can study the functional role of NCBP3 in various biological processes, including RNA metabolism, immune response, and cellular stress, making these lines invaluable tools in molecular biology.

The primary mechanisms through which NCBP3 influences cellular function can be outlined by its role in the nuclear-cytoplasmic transport of mRNA and its involvement in the regulation of protein synthesis. By utilizing these knockout cell lines, researchers can investigate the consequences of NCBP3 loss—such as altered gene expression profiles, impaired cellular signaling pathways, and modified stress responses—enabling comprehensive studies that reveal the significance of this gene in health and disease.

The scientific importance of NCBP3 Gene Knockout Cell Lines extends beyond basic research; they possess significant applications in clinical settings, particularly in drug discovery and development. Understanding the pathophysiological implications of NCBP3 dysfunction could pave the way for new therapeutics targeting mRNA modulation in diseases such as cancer and viral infections.

What sets NCBP3 Gene Knockout Cell Lines apart from alternative models is their specificity and the precise nature of gene targeting, which allows for reproducible results and greater reliability in experimental outcomes. Additionally, these cell lines are readily available in various backgrounds, granting researchers the flexibility to choose the most appropriate model for their experimental designs.

By opting for NCBP3 Gene Knockout Cell Lines, researchers and clinicians can leverage a powerful tool that simplifies the investigation of gene functions, providing critical insights into cellular biology and disease mechanisms. Our company specializes in delivering high-quality biological products, underpinned by a commitment to cutting-edge research and innovative solutions that empower scientific discovery.

Please note that all services are for research use only. Not intended for any clinical use.

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