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NAXE Knockout Cell Lines

Gene: NAXE

Official Full Name: NAD(P)HX epimeraseprovided by HGNC

Gene Summary: The product of this gene interacts with apolipoprotein A-I (apoA-I), the major apolipoprotein of high-density lipoproteins (HDLs). It is secreted into some bodily fluids, and its synthesis and secretion are stimulated in vitro by incubating cells with apoA-I. The human genome contains related pseudogenes. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO15859 NAXE Knockout cell line (HeLa) Human NAXE 1:3~1:6 Negative Online Inquiry
KO15860 NAXE Knockout cell line (HCT 116) Human NAXE 1:2~1:4 Negative Online Inquiry
KO15861 NAXE Knockout cell line (HEK293) Human NAXE 1:3~1:6 Negative Online Inquiry
KO15862 NAXE Knockout cell line (A549) Human NAXE 1:3~1:4 Negative Online Inquiry

Background

NAXE Gene Knockout Cell Lines are genetically engineered cellular models designed to facilitate the study of the NAXE gene's role in various biological processes. These cell lines are developed using state-of-the-art CRISPR-Cas9 technology to create precise gene knockouts, enabling researchers to investigate the functional consequences of NAXE deficiency on cellular mechanisms and signaling pathways. The targeted disruption of this gene allows scientists to assess the implications of NAXE in metabolic processes, cellular stress responses, and disease states, making these cell lines invaluable tools for molecular biology and genetics research.

The key function of NAXE is its involvement in nicotinamide adenine dinucleotide (NAD) metabolism, which is critical for cellular redox balance and energy production. By using NAXE Gene Knockout Cell Lines, researchers can explore the effects of NAXE loss on NAD-associated metabolic pathways, revealing potential connections to age-related diseases and conditions such as cancer or neurodegeneration. These insights are particularly relevant in clinical research, as understanding the role of NAXE could lead to novel therapeutic strategies aimed at managing metabolic disorders or enhancing cell survival during stress.

One of the distinct advantages of our NAXE Gene Knockout Cell Lines is their reliability and consistency compared to alternative models, such as transient knockdown approaches or other knockout strategies that may not provide stable genetic modifications. Our cell lines come with comprehensive characterization data, ensuring a robust platform for experimental reproducibility. Additionally, they are already optimized for a variety of culture conditions, minimizing the time and resources required for adaptation and initial setup.

Researchers and clinicians will find value in using NAXE Gene Knockout Cell Lines due to their potential to elucidate critical biochemical pathways and facilitate drug discovery efforts targeting NAD metabolism. The combination of customizability in experimental design and our assurance of quality makes these cell lines a superior choice for advancing scientific inquiry.

Our company is recognized for its expertise in developing high-quality biological products tailored to meet the evolving needs of the research community. With a commitment to innovation and reliability, we provide researchers with the tools necessary to drive discovery and enhance our understanding of complex biological systems.

Please note that all services are for research use only. Not intended for any clinical use.

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