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MYORG Knockout Cell Lines

Gene: MYORG

Official Full Name: myogenesis regulating glycosidaseprovided by HGNC

Gene Summary: Predicted to enable hydrolase activity, hydrolyzing O-glycosyl compounds. Involved in skeletal muscle fiber development. Predicted to be located in endoplasmic reticulum membrane and nuclear membrane. Implicated in basal ganglia calcification. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO20192 MYORG Knockout cell line (HeLa) Human MYORG 1:3~1:6 Negative Online Inquiry
KO20193 MYORG Knockout cell line (HCT 116) Human MYORG 1:2~1:4 Negative Online Inquiry
KO20194 MYORG Knockout cell line (HEK293) Human MYORG 1:3~1:6 Negative Online Inquiry
KO20195 MYORG Knockout cell line (A549) Human MYORG 1:3~1:4 Negative Online Inquiry

Background

MYORG Gene Knockout Cell Lines are an advanced suite of genetically modified cell lines specifically designed to facilitate the study of gene function and regulation. Utilizing CRISPR/Cas9 gene editing technology, these cell lines provide researchers with a powerful tool to create precise knockouts of target genes, thus enabling the dissection of molecular pathways and the evaluation of gene-related phenotypes in various biological contexts.

The primary mechanism of MYORG Gene Knockout Cell Lines involves the site-specific introduction of double-strand breaks in the DNA, which initiates the cell’s repair processes. Through non-homologous end joining, inaccuracies in the repair can lead to frameshift mutations, effectively silencing the target gene. This allows researchers to observe both loss-of-function effects and the resultant physiological changes, thus shedding light on gene interactions and cellular mechanisms.

The scientific importance of these knockout models extends across multiple fields, including cancer research, developmental biology, and drug discovery. They have applications in elucidating disease mechanisms, identifying potential therapeutic targets, and screening new compounds for efficacy in gene-affected pathways. In clinical settings, these cell lines can serve as platforms for precision medicine by providing patient-derived models for testing drug responses specific to genetic mutations.

One of the standout advantages of MYORG Gene Knockout Cell Lines is their validation in diverse cellular environments, ensuring robust, reproducible results. Compared to alternative models, such as traditional RNA interference methods, which can result in off-target effects, our knockout lines offer greater specificity and durability in gene disruption. This enhances the reliability of experimental outcomes and accelerates the research timeline.

For researchers and clinicians, the capacity to manipulate gene expression with precision directly translates to the potential for groundbreaking discoveries and innovations in treatment strategies. The adaptability of our knockout lines to various experimental setups makes them invaluable tools in advancing research efforts.

As a leader in the field of molecular biology products, our commitment to providing high-quality, meticulously validated gene knockout cell lines reflects our deep expertise and dedication to supporting the research community. By choosing MYORG Gene Knockout Cell Lines, users are equipped with the necessary resources to transform their genetic studies into reliable and impactful scientific advancements.

Please note that all services are for research use only. Not intended for any clinical use.

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