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MSL2 Knockout Cell Lines

Gene: MSL2

Official Full Name: MSL complex subunit 2provided by HGNC

Gene Summary: Enables histone H2B ubiquitin ligase activity. Involved in DNA damage response and protein monoubiquitination. Part of MSL complex and nucleus. Is active in chromatin. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO16001 MSL2 Knockout cell line (HeLa) Human MSL2 1:3~1:6 Negative Online Inquiry
KO16002 MSL2 Knockout cell line (HCT 116) Human MSL2 1:2~1:4 Negative Online Inquiry
KO16003 MSL2 Knockout cell line (HEK293) Human MSL2 1:3~1:6 Negative Online Inquiry
KO16004 MSL2 Knockout cell line (A549) Human MSL2 1:3~1:4 Negative Online Inquiry

Background

MSL2 Gene Knockout Cell Lines are genetically engineered cellular models that have had the MSL2 gene specifically disrupted or deleted. MSL2, or Male-Specific Lethal 2, is a crucial component involved in the regulation of gene expression and chromatin modification, particularly in the context of X-chromosome dosage compensation in Drosophila and potential implications in mammalian systems. These knockout cell lines provide researchers with a powerful tool to investigate the functional roles of the MSL2 gene, as well as its impact on cellular processes such as proliferation, differentiation, and response to various stimuli.

The primary function of MSL2 involves modulating the transcriptional landscape by modifying histones and facilitating the assembly of protein complexes that mark the X-chromosome for enhanced expression. By utilizing these knockout models, scientists can elucidate the pathways impacted by MSL2, further understanding its role in developmental biology and disease processes, such as cancer and genetic disorders. Such insights have significant implications for both basic research and clinical applications, paving the way for targeted therapies and new methodologies in gene therapy.

What sets our MSL2 Gene Knockout Cell Lines apart from other models is their authenticity and reliability, developed using state-of-the-art CRISPR-Cas9 gene-editing technology. This approach ensures precise and complete knockout of the MSL2 gene, providing unparalleled specificity in research. Unlike traditional cell lines that may harbor multiple genetic variations or mutations, our knockout lines offer homogeneity, assuring that experimental results are solely attributable to the MSL2 gene's absence.

The value of these cell lines cannot be overstated; they not only streamline experimental workflows but also enhance reproducibility and accuracy of results, which are crucial for hypothesis testing and validation. Researchers, clinicians, and biotechnology companies can leverage these models to accelerate their studies in gene function and regulation, thereby driving innovation in therapeutic approaches.

Our company prides itself on offering high-quality biological products, fortified by extensive expertise in genetic engineering and cell biology. Committed to advancing research, we provide reliable, precisely engineered cell line solutions that meet the evolving needs of the scientific community.

Please note that all services are for research use only. Not intended for any clinical use.

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