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MPRIP Knockout Cell Lines

Gene: MPRIP

Official Full Name: myosin phosphatase Rho interacting proteinprovided by HGNC

Gene Summary: Enables cadherin binding activity. Located in actin cytoskeleton and cytosol. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO04536 MPRIP Knockout cell line (HeLa) Human MPRIP 1:3~1:6 Negative Online Inquiry
KO04537 MPRIP Knockout cell line (HCT 116) Human MPRIP 1:2~1:4 Negative Online Inquiry
KO04538 MPRIP Knockout cell line (HEK293) Human MPRIP 1:3~1:6 Negative Online Inquiry
KO04539 MPRIP Knockout cell line (A549) Human MPRIP 1:3~1:4 Negative Online Inquiry

Background

MPRIP Gene Knockout Cell Lines are specialized cellular models engineered to silence the expression of the MPRIP (MARCKS-related protein interacting protein) gene, providing researchers with a powerful tool for investigating the role of this protein in various biological processes. These cell lines utilize CRISPR-Cas9 technology to achieve precise gene knockout, allowing for in-depth studies of MPRIP's function in cellular signaling, cytoskeletal dynamics, and disease pathogenesis.

The primary function of the MPRIP gene revolves around its interaction with various cellular components, notably in the context of regulating actin-myosin contractility. By disrupting MPRIP expression, these knockout cell lines enable researchers to elucidate the pathways influenced by MPRIP, including those related to cell migration, proliferation, and intracellular signaling cascades. The potential mechanisms at play can yield insights into cancer metastasis, cardiovascular diseases, and neurological disorders, making this product highly relevant in both basic and applied biomedical research.

The scientific importance of MPRIP Gene Knockout Cell Lines lies in their ability to facilitate the examination of pathological states where MPRIP dysregulation is implicated. These cell lines offer a unique opportunity to model diseases that may be linked to the aberrant expression or function of MPRIP, making them invaluable for therapeutic research and drug development.

Compared to alternative models, MPRIP Gene Knockout Cell Lines provide researchers with a precise and reproducible system that mimics native cellular environments while eliminating the confounding variables associated with overexpression systems or non-targeted gene disruption. This specificity enhances the reliability of experimental outcomes and paves the way for novel discoveries related to MPRIP’s biological significance.

For researchers and clinicians, these knockout cell lines represent a critical resource for exploring the underlying mechanisms of diseases, assessing drug efficacy, and developing innovative therapeutic approaches. Leveraging expertise in molecular biology and state-of-the-art gene editing technologies, our company is dedicated to offering high-quality biological products, ensuring our clients have access to the essential tools needed for advancing their research endeavors in the life sciences.

Please note that all services are for research use only. Not intended for any clinical use.

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