Gene: MOCS2
Official Full Name: molybdenum cofactor synthesis 2provided by HGNC
Gene Summary: Eukaryotic molybdoenzymes use a unique molybdenum cofactor (MoCo) consisting of a pterin, termed molybdopterin, and the catalytically active metal molybdenum. MoCo is synthesized from precursor Z by the heterodimeric enzyme molybdopterin synthase. The large and small subunits of molybdopterin synthase are both encoded from this gene by overlapping open reading frames. The proteins were initially thought to be encoded from a bicistronic transcript. They are now thought to be encoded from monocistronic transcripts. Alternatively spliced transcripts have been found for this locus that encode the large and small subunits. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO36584 | MOCS2 Knockout cell line (HeLa) | Human | MOCS2 | 1:3~1:6 | Negative | Online Inquiry |
KO36585 | MOCS2 Knockout cell line (HCT 116) | Human | MOCS2 | 1:2~1:4 | Negative | Online Inquiry |
KO36586 | MOCS2 Knockout cell line (HEK293) | Human | MOCS2 | 1:3~1:6 | Negative | Online Inquiry |
KO36587 | MOCS2 Knockout cell line (A549) | Human | MOCS2 | 1:3~1:4 | Negative | Online Inquiry |
MOCS2 Gene Knockout Cell Lines are genetically engineered cell lines designed to study the biological role of the MOCS2 gene, which is crucial in the biosynthesis of molybdenum cofactors. These specialized cell lines facilitate the investigation of MOCS2's involvement in cellular processes, such as sulfur metabolism and its implications in various human diseases, including neurological disorders.
The key function of MOCS2 gene knockout cell lines is to provide a platform for researchers to model the effects of MOCS2 deficiency, allowing for the examination of cellular responses at the molecular and pathway levels. By eliminating the MOCS2 gene, these cell lines enable the dissection of regulatory mechanisms that lead to alterations in metabolic pathways and inform how these changes contribute to disease pathology. Additionally, the use of CRISPR-Cas9 technology in generating these knockout lines ensures precision and efficiency, allowing for reproducible results across experiments.
In research and clinical settings, MOCS2 gene knockout cell lines play a pivotal role in molecular biology and genetic studies. They are particularly valuable for drug discovery and development, providing insights into potential therapeutic targets for conditions linked to metabolic dysregulation. Their ability to mimic human physiological responses enhances their relevance for translational research.
Compared to traditional models, MOCS2 knockout cell lines offer a unique selling point by presenting a more precise model system that reduces genetic variability and improves experimental fidelity. While other models may not adequately reflect the complexity of MOCS2's functions, these tailored cell lines deliver a focused approach for studying its impacts.
For researchers and clinicians, MOCS2 gene knockout cell lines represent an invaluable tool, bridging the gap between basic science and clinical application. Our company, with its commitment to advancing genetic resources in biomedical research, provides these expertly curated cell lines to empower breakthroughs in understanding and treating diseases linked to MOCS2 dysfunction.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.