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MLXIP Knockout Cell Lines

Gene: MLXIP

Official Full Name: MLX interacting proteinprovided by HGNC

Gene Summary: This gene encodes a protein that functions as part of a heterodimer to activate transcription. The encoded protein forms a heterodimer with Max-like protein X (MLX) and is involved in the regulation of genes in response to cellular glucose levels. [provided by RefSeq, Mar 2014]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO30224 MLXIP Knockout cell line (HeLa) Human MLXIP 1:3~1:6 Negative Online Inquiry
KO30225 MLXIP Knockout cell line (HCT 116) Human MLXIP 1:2~1:4 Negative Online Inquiry
KO30226 MLXIP Knockout cell line (HEK293) Human MLXIP 1:3~1:6 Negative Online Inquiry
KO30227 MLXIP Knockout cell line (A549) Human MLXIP 1:3~1:4 Negative Online Inquiry

Background

MLXIP Gene Knockout Cell Lines are specifically engineered cellular models designed to facilitate the study of MLXIP (Max-Like Protein X-Interacting Protein), a transcription factor involved in various metabolic pathways and cellular processes. These cell lines enable researchers to investigate the downstream effects of MLXIP deletion on gene expression, metabolic regulation, and cellular response to stress, thereby providing critical insights into the gene's role in conditions such as obesity, diabetes, and cancer.

The key function of the MLXIP Gene Knockout Cell Lines is to allow for the observation of phenotypic changes associated with the absence of MLXIP. Utilizing CRISPR-Cas9 gene editing technology, these cell lines exhibit complete knockout of the MLXIP gene, ensuring reproducibility and accuracy in experimental outcomes. As a result, researchers can closely examine the cascading effects on metabolic signaling pathways and other gene interactions that may contribute to pathological states.

In terms of scientific importance, MLXIP Gene Knockout Cell Lines serve as invaluable tools in both basic research and clinical investigations. They enable scientists to elucidate the biological functions of MLXIP and assess potential therapeutic targets. By understanding its role in cellular metabolism, researchers can innovate new strategies to combat metabolic disorders and improve treatment regimens for related diseases.

What sets MLXIP Gene Knockout Cell Lines apart from alternative models is their precision and reliability. Unlike traditional methods, which may rely on transient or incomplete knockdown strategies, these stable knockout lines ensure a consistent phenotype and improved data quality. Additionally, they are derived from widely-used cellular backgrounds, making them compatible with a range of experimental conditions and assays.

For researchers and clinicians seeking to advance their understanding of metabolic diseases, MLXIP Gene Knockout Cell Lines offer a unique opportunity to dissect the complexities of gene function, with the potential to translate findings into impactful clinical applications. Our company is dedicated to advancing biological research through high-quality, rigorously validated products, and MLXIP Gene Knockout Cell Lines embody our commitment to excellence in scientific innovation.

Please note that all services are for research use only. Not intended for any clinical use.

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