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MLEC Knockout Cell Lines

Gene: MLEC

Official Full Name: malectinprovided by HGNC

Gene Summary: This gene encodes the carbohydrate-binding protein malectin which is a Type I membrane-anchored endoplasmic reticulum protein. This protein has an affinity for Glc2Man9GlcNAc2 (G2M9) N-glycans and is involved in regulating glycosylation in the endoplasmic reticulum. This protein has also been shown to interact with ribophorin I and may be involved in the directing the degradation of misfolded proteins. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO02825 MLEC Knockout cell line (HeLa) Human MLEC 1:3~1:6 Negative Online Inquiry
KO02826 MLEC Knockout cell line (HCT 116) Human MLEC 1:2~1:4 Negative Online Inquiry
KO02827 MLEC Knockout cell line (HEK293) Human MLEC 1:3~1:6 Negative Online Inquiry
KO02828 MLEC Knockout cell line (A549) Human MLEC 1:3~1:4 Negative Online Inquiry

Background

MLEC Gene Knockout Cell Lines are a specialized biotechnological product designed for the precise study of gene function and regulation in mammalian cells. These cell lines are generated using advanced CRISPR/Cas9 technology, which allows for targeted disruption of specific genes, creating cellular models that lack the expression of particular proteins. This gene knockout capability provides researchers with a powerful tool for investigating the biological roles of genes, elucidating disease mechanisms, and screening for potential therapeutic targets.

The key mechanism behind MLEC Gene Knockout Cell Lines involves the introduction of double-strand breaks in the DNA at predetermined loci, followed by the cell's natural repair processes, which can lead to the insertion of mutations that effectively silence gene expression. By providing a range of cell types that have been validated for specific gene knockout, these cell lines enable detailed functional studies, including analyses of pathways involving proliferation, apoptosis, and metabolic changes.

The scientific importance of MLEC Gene Knockout Cell Lines cannot be overstated, as they are invaluable in both research and clinical settings. They are widely used in fundamental biological research, drug development, and pre-clinical studies, allowing scientists to model human diseases, validate gene function, and assess the efficacy of novel therapies in a controlled environment.

One of the standout advantages of MLEC Gene Knockout Cell Lines is their reliability and reproducibility. Each cell line undergoes extensive characterization to confirm gene knockout efficacy and stability over multiple passages, setting them apart from alternative approaches that may lead to inconsistent results. Moreover, their adaptability to diverse experimental workflows provides users the flexibility to integrate them into a variety of research disciplines, from cancer biology to regenerative medicine.

For researchers and clinicians seeking robust models that facilitate hypothesis testing and therapeutic development, MLEC Gene Knockout Cell Lines represent an essential addition to the laboratory toolkit. Their ability to deliver clear insights into gene function and interactions drives innovation and fosters scientific discovery.

At [Your Company Name], we pride ourselves on our expertise in developing cutting-edge biological products, ensuring that our solutions meet the highest standards of quality, reliability, and scientific integrity. Our commitment to advancing research through innovative technologies makes us a trusted partner in the pursuit of knowledge in the life sciences.

Please note that all services are for research use only. Not intended for any clinical use.

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