Gene: METTL13
Official Full Name: methyltransferase 13, eEF1A N-terminus and K55provided by HGNC
Gene Summary: Enables protein-lysine N-methyltransferase activity. Predicted to be involved in methylation. Located in cytosol. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO16228 | METTL13 Knockout cell line (HeLa) | Human | METTL13 | 1:3~1:6 | Negative | Online Inquiry |
KO16229 | METTL13 Knockout cell line (HCT 116) | Human | METTL13 | 1:2~1:4 | Negative | Online Inquiry |
KO16230 | METTL13 Knockout cell line (HEK293) | Human | METTL13 | 1:3~1:6 | Negative | Online Inquiry |
KO16231 | METTL13 Knockout cell line (A549) | Human | METTL13 | 1:3~1:4 | Negative | Online Inquiry |
METTL13 Gene Knockout Cell Lines are genetically modified cell cultures designed to facilitate the study of the METTL13 gene, which encodes a methyltransferase involved in RNA modification. The disruption of this gene allows researchers to investigate its role in cellular processes, such as RNA metabolism, gene expression regulation, and cellular stress response. By using CRISPR/Cas9 technology, these knockout cell lines provide a highly efficient and specific means to elucidate the function of METTL13 while minimizing off-target effects.
The key functions of the METTL13 gene are primarily involved in the modulation of mRNA translation and stability through N6-methyladenosine (m6A) modification. This precise control over RNA modification can significantly influence protein synthesis, cellular signaling pathways, and overall cellular health. Consequently, the METTL13 Gene Knockout Cell Lines serve as invaluable tools in both fundamental research and therapeutic development, enabling scientists to explore the underlying mechanisms of diseases such as cancer, neurodegeneration, and metabolic disorders.
The scientific importance of these cell lines is underscored by their applications in drug discovery, biomarker identification, and the investigation of gene regulation networks. By providing a clear model to study the absence of METTL13 function, researchers can gain insights into therapeutic targets and potential intervention strategies.
In comparison to traditional cell lines, METTL13 Gene Knockout Cell Lines offer distinct advantages such as precise genetic manipulation, biological relevance, and reproducibility. Researchers benefit from reliable experimental conditions that highlight the effects of METTL13 disruption, which can be pivotal in elucidating the complex interactions within the cell.
For researchers and clinicians alike, these knockout cell lines represent a significant value proposition in advancing our understanding of RNA biology and disease mechanisms. Our company is committed to delivering high-quality, genetically tailored cell lines that empower groundbreaking research. With expertise in genetic engineering and a portfolio encompassing various cellular models, we stand at the forefront of innovations that drive scientific discovery forward.
Please note that all services are for research use only. Not intended for any clinical use.
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