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MBLAC1 Knockout Cell Lines

Gene: MBLAC1

Official Full Name: metallo-beta-lactamase domain containing 1provided by HGNC

Gene Summary: Enables RNA endonuclease activity and metal ion binding activity. Involved in histone mRNA metabolic process; mRNA 3'-end processing; and positive regulation of G1/S transition of mitotic cell cycle. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO21103 MBLAC1 Knockout cell line (HeLa) Human MBLAC1 1:3~1:6 Negative Online Inquiry
KO21104 MBLAC1 Knockout cell line (HCT 116) Human MBLAC1 1:2~1:4 Negative Online Inquiry
KO21105 MBLAC1 Knockout cell line (HEK293) Human MBLAC1 1:3~1:6 Negative Online Inquiry
KO21106 MBLAC1 Knockout cell line (A549) Human MBLAC1 1:3~1:4 Negative Online Inquiry

Background

MBLAC1 Gene Knockout Cell Lines are genetically modified cellular systems that specifically lack the MBLAC1 gene, known for its involvement in the regulation of various cellular processes. These knockout cell lines serve as invaluable tools for researchers aiming to dissect the functional roles of the MBLAC1 gene in diverse biological contexts. By providing a platform devoid of the MBLAC1 protein's influence, scientists can investigate the gene's contribution to mechanisms such as cell signaling, apoptosis, and metabolic regulation.

The key function of MBLAC1 gene knockout cell lines lies in their ability to facilitate the study of gene function through loss-of-function analysis. Utilizing advanced CRISPR/Cas9 technology, these cell lines exhibit complete knockout of the MBLAC1 gene, enabling a thorough examination of downstream effects and compensatory pathways that may emerge due to its absence. Such detailed insights are critical for elucidating the gene's role in normal physiology and its potential implications in various diseases.

Scientifically, MBLAC1 gene knockout cell lines have broad applications in both basic research and clinical settings. They can be used to model common disease states, explore drug responses, and develop therapeutic strategies targeting MBLAC1-associated pathways. This capability enhances our understanding of conditions like cancer and metabolic disorders, where MBLAC1 dysregulation is implicated.

Compared to existing alternatives, like wild-type cell lines or less specific knockdown models, the MBLAC1 gene knockout cell lines offer specificity and robustness. They allow for clearer interpretation of data related to the MBLAC1 gene without the confounding effects from residual gene expression. This clarity greatly benefits the reproducibility of research findings.

For researchers and clinicians seeking to explore the intricate biology surrounding the MBLAC1 gene, these knockout cell lines offer unparalleled research precision and insight. Our company prides itself on its commitment to providing high-quality, genetically engineered models that empower the scientific community. We leverage our expertise in genetic engineering and cell line development to deliver advanced tools that foster innovative research and therapeutic advancements.

Please note that all services are for research use only. Not intended for any clinical use.

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