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MAP3K6 Knockout Cell Lines

Gene: MAP3K6

Official Full Name: mitogen-activated protein kinase kinase kinase 6provided by HGNC

Gene Summary: This gene encodes a serine/threonine protein kinase that forms a component of protein kinase-mediated signal transduction cascades. The encoded kinase participates in the regulation of vascular endothelial growth factor (VEGF) expression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO10674 MAP3K6 Knockout cell line (HeLa) Human MAP3K6 1:3~1:6 Negative Online Inquiry
KO10675 MAP3K6 Knockout cell line (HCT 116) Human MAP3K6 1:2~1:4 Negative Online Inquiry
KO10676 MAP3K6 Knockout cell line (HEK293) Human MAP3K6 1:3~1:6 Negative Online Inquiry
KO10677 MAP3K6 Knockout cell line (A549) Human MAP3K6 1:3~1:4 Negative Online Inquiry

Background

MAP3K6 Gene Knockout Cell Lines represent a pivotal advancement in genetic research, providing scientists with a tool to investigate the functional role of the MAP3K6 gene in cellular processes. These cell lines are engineered through CRISPR-Cas9 technology to disrupt the MAP3K6 gene, resulting in a knockout that allows researchers to explore the gene's involvement in diverse biological pathways, including stress responses, cell proliferation, and apoptosis.

The primary function of these cell lines lies in their ability to facilitate loss-of-function studies, enabling the evaluation of MAP3K6's contributions to various cellular mechanisms. By observing phenotypic differences between knockout and wild-type cells, researchers can decipher the specific roles of MAP3K6 in pathophysiological conditions such as cancer, neurodegenerative disorders, and cardiovascular diseases.

From a scientific perspective, MAP3K6 Gene Knockout Cell Lines hold significant value in both basic and applied research. They are essential for drug discovery initiatives by allowing screening for compounds that target MAP3K6-related pathways, and for validating therapeutic strategies based on MAP3K6 modulation. Their utility extends into the realm of synthetic biology, where understanding gene functions is crucial for engineering cellular systems.

Compared to conventional knockout methods, our MAP3K6 Gene Knockout Cell Lines offer enhanced precision and reliability due to the specificity of the CRISPR-Cas9 technique. Additionally, they are optimized for high-throughput screening, making them ideal for comprehensive studies across multiple experimental conditions.

For researchers and clinicians, the value of these cell lines lies in their ability to streamline investigations and provide deeper insights into gene functionality, ultimately driving forward scientific knowledge and therapeutic development. As a company dedicated to advancing genetic research, we specialize in cutting-edge cell line technologies that empower the scientific community to unlock the complexities of gene regulation and expression. Our expertise ensures that every product we offer meets the highest standards of quality and reliability, supporting your research goals with confidence.

Please note that all services are for research use only. Not intended for any clinical use.

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