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LRRC40 Knockout Cell Lines

Gene: LRRC40

Official Full Name: leucine rich repeat containing 40provided by HGNC

Gene Summary: Predicted to be involved in intracellular signal transduction. Located in membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO16458 LRRC40 Knockout cell line (HeLa) Human LRRC40 1:3~1:6 Negative Online Inquiry
KO16459 LRRC40 Knockout cell line (HCT 116) Human LRRC40 1:2~1:4 Negative Online Inquiry
KO16460 LRRC40 Knockout cell line (HEK293) Human LRRC40 1:3~1:6 Negative Online Inquiry
KO16461 LRRC40 Knockout cell line (A549) Human LRRC40 1:3~1:4 Negative Online Inquiry

Background

LRRC40 Gene Knockout Cell Lines are genetically engineered cell lines characterized by the precise disruption of the LRRC40 gene, a crucial component involved in several biological processes, including cellular signaling and immune response modulation. These cell lines utilize advanced CRISPR-Cas9 technology to create targeted deletions that render the LRRC40 gene inactive, enabling researchers to effectively study the gene's role in disease mechanisms and therapeutic responses.

The primary function of these knockout cell lines is to serve as a robust platform for investigating the biological implications of LRRC40 absence. By comparing the phenotypic and genotypic characteristics of these knockout models to their wild-type counterparts, scientists can gain insights into cellular pathways influenced by LRRC40 regulation. The loss of this gene is particularly critical in studies related to immune system functions, where it may influence the responsiveness of immune cells to various stimuli.

In research and clinical settings, LRRC40 Gene Knockout Cell Lines hold significant value for drug discovery and development. They enable high-throughput screening of pharmaceutical compounds aimed at modulating pathways associated with LRRC40, potentially leading to novel therapeutic strategies for autoimmune diseases or cancer. Additionally, these models facilitate the examination of gene interactions within cellular networks, providing deeper understanding necessary for precision medicine.

Compared to alternative models, such as siRNA or transient transfection systems, our LRRC40 Gene Knockout Cell Lines offer enhanced stability and reproducibility of results due to the permanent genetic alteration. The CRISPR-Cas9 technique ensures high specificity and efficiency, minimizing off-target effects, which is critical for obtaining reliable experimental data.

The intrinsic value of using LRRC40 Gene Knockout Cell Lines lies in their potential to accelerate research and development efforts, thereby contributing to breakthroughs in understanding diseases impacted by the LRRC40 gene. This is particularly advantageous for researchers and clinicians looking for advanced tools to dissect complex biological interactions and develop targeted treatments.

Our company is dedicated to providing high-quality, scientifically validated biological products, and our expertise in gene editing technologies ensures that our LRRC40 Gene Knockout Cell Lines meet the rigorous standards required for cutting-edge research and clinical applications.

Please note that all services are for research use only. Not intended for any clinical use.

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