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LRIG1 Knockout Cell Lines

Gene: LRIG1

Official Full Name: leucine rich repeats and immunoglobulin like domains 1provided by HGNC

Gene Summary: Predicted to act upstream of or within several processes, including innervation; otolith morphogenesis; and sensory perception of sound. Predicted to be located in plasma membrane. Predicted to be active in extracellular matrix and extracellular space. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO28475 LRIG1 Knockout cell line (HeLa) Human LRIG1 1:3~1:6 Negative Online Inquiry
KO28476 LRIG1 Knockout cell line (HCT 116) Human LRIG1 1:2~1:4 Negative Online Inquiry
KO28477 LRIG1 Knockout cell line (HEK293) Human LRIG1 1:3~1:6 Negative Online Inquiry
KO28478 LRIG1 Knockout cell line (A549) Human LRIG1 1:3~1:4 Negative Online Inquiry

Background

LRIG1 Gene Knockout Cell Lines are a powerful tool for studying the functional roles of the LRIG1 gene, renowned for its involvement in cell proliferation, differentiation, and tumor suppression. These cell lines have been meticulously engineered using CRISPR-Cas9 technology to provide a precise inactivation of LRIG1, allowing researchers to investigate its biological functions with unparalleled accuracy.

The primary mechanism of action involves the targeted modification of the LRIG1 gene, resulting in the complete loss of protein expression. This enables the exploration of downstream signaling pathways and cellular processes influenced by LRIG1. Researchers can employ these knockout cell lines to delve into the consequences of LRIG1 loss on cellular behavior, including its impact on oncogenic signaling, migration, and apoptosis. The utility of LRIG1 knockout cell lines extends to diverse fields, from cancer biology to regenerative medicine, providing critical insights that can inform therapeutic strategies.

In clinical and research environments, these cell lines serve as invaluable resources for drug discovery, biomarker identification, and preclinical testing. Their specificity in gene editing alleviates common concerns associated with off-target effects, enhancing the reliability of experimental results. Compared to traditional gene silencing methods such as siRNA or shRNA, LRIG1 Gene Knockout Cell Lines offer a more stable and permanent modification, thereby facilitating long-term studies.

For researchers and clinicians, the ability to manipulate the LRIG1 gene presents substantial implications for understanding disease mechanisms and developing targeted interventions. Our company, recognized for its commitment to advancing genomic technologies, proudly offers these rigorously validated cell lines. With expertise in precision genetics and a broad array of biological products, we remain dedicated to supporting the scientific community in their quest for groundbreaking discoveries.

Please note that all services are for research use only. Not intended for any clinical use.

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