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LPAR5 Knockout Cell Lines

Gene: LPAR5

Official Full Name: lysophosphatidic acid receptor 5provided by HGNC

Gene Summary: This gene encodes a member of the rhodopsin class of G protein-coupled transmembrane receptors. This protein transmits extracellular signals from lysophosphatidic acid to cells through heterotrimeric G proteins and mediates numerous cellular processes. Many G protein receptors serve as targets for pharmaceutical drugs. Transcript variants of this gene have been described.[provided by RefSeq, Dec 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO08825 LPAR5 Knockout cell line (HeLa) Human LPAR5 1:3~1:6 Negative Online Inquiry
KO08826 LPAR5 Knockout cell line (HCT 116) Human LPAR5 1:2~1:4 Negative Online Inquiry
KO08827 LPAR5 Knockout cell line (A549) Human LPAR5 1:3~1:4 Negative Online Inquiry

Background

LPAR5 Gene Knockout Cell Lines are a specialized tool designed for research focused on the function and implications of the LPAR5 gene, also known as the lysophosphatidic acid receptor 5. These cell lines have been genetically engineered to have a complete knockout of the LPAR5 gene, enabling researchers to investigate the physiological and pathological roles of this particular receptor without the confounding effects of its normal activity.

The primary function of these knockout cell lines is to provide a controlled platform to study the downstream signaling pathways activated by lysophosphatidic acid (LPA) in a physiological context, including cell proliferation, migration, and invasion. By eliminating LPAR5 expression, researchers can delineate the receptor-specific responses in various biological processes, laying the groundwork for further studies into diseases such as cancer, fibrosis, and neurodegeneration, where LPA signaling is implicated.

The scientific importance of LPAR5 Gene Knockout Cell Lines lies in their ability to facilitate a deeper understanding of receptor biology and its contributions to disease mechanisms. These models are essential in drug discovery and therapeutic development, particularly in identifying novel targets for intervention in diseases driven by aberrant LPA signaling.

Compared to traditional cell lines, these knockout models offer clear advantages, including increased specificity and reduced background noise in signaling assays, leading to more reliable data. The precision of these models allows for robust reproducibility in experimental results, which is critical for advancing research in the field.

Researchers and clinicians will find LPAR5 Gene Knockout Cell Lines invaluable for high-quality, reproducible studies that can significantly impact drug development and personalized medicine approaches. Investing in these cell lines supports a commitment to cutting-edge research and fosters advancements that align with clinical needs.

Our company specializes in providing high-quality genetic models and biological products tailored to support research excellence. With expertise in cell line development and a commitment to innovation, we empower scientists to explore new frontiers in biology and medicine.

Please note that all services are for research use only. Not intended for any clinical use.

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