Gene: LMAN2
Official Full Name: lectin, mannose binding 2provided by HGNC
Gene Summary: This gene encodes a type I transmembrane lectin that shuttles between the endoplasmic reticulum, the Golgi apparatus and the plasma membrane. The encoded protein binds high mannose type glycoproteins and may facilitate their sorting, trafficking and quality control. [provided by RefSeq, Oct 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO02186 | LMAN2 Knockout cell line (HeLa) | Human | LMAN2 | 1:3~1:6 | Negative | Online Inquiry |
KO02187 | LMAN2 Knockout cell line (HCT 116) | Human | LMAN2 | 1:2~1:4 | Negative | Online Inquiry |
KO02188 | LMAN2 Knockout cell line (HEK293) | Human | LMAN2 | 1:3~1:6 | Negative | Online Inquiry |
KO02189 | LMAN2 Knockout cell line (A549) | Human | LMAN2 | 1:3~1:4 | Negative | Online Inquiry |
LMAN2 Gene Knockout Cell Lines are precisely engineered cellular models that have had the LMAN2 gene disrupted to investigate the role of this gene in various biological processes. LMAN2, or lectin mannose-binding 2, is involved in the transport of glycoproteins within the cell. By generating knockout lines, researchers can elucidate the gene's function and its implications in health and disease, particularly in metabolism and immune responses.
The primary function of these knockout cell lines is to serve as a versatile tool for functional genomics studies. By observing the phenotypic characteristics of LMAN2-deficient cells, researchers can gain insights into how this gene impacts cellular transport mechanisms and the subsequent effect on disease pathways. The genome editing techniques employed ensure a complete loss of LMAN2 function, allowing scientists to identify compensatory pathways and dissect molecular interactions that are otherwise masked in wild-type cells.
In the realm of scientific research, LMAN2 knockout cell lines hold significant potential for advancing our understanding of glycoprotein metabolism and its connection to diseases such as cancer and lysosomal storage disorders. These models also facilitate drug discovery efforts by providing insights into potential gene targets and enabling pharmacological assessments.
What sets our LMAN2 Gene Knockout Cell Lines apart from alternative products is their high specificity, reliability, and the convenience of use in various assay systems, such as those assessing cytotoxicity, immunological responses, or metabolic pathways. Additionally, our production process adheres to stringent quality controls, ensuring robust performance and reproducibility.
For researchers and clinicians looking to unravel the complexities of gene function and its implications in health and disease, our LMAN2 Gene Knockout Cell Lines offer an invaluable resource. With a commitment to excellence in biological products, our company leverages years of expertise in genetic engineering, enabling the scientific community to advance their research with confidence.
Please note that all services are for research use only. Not intended for any clinical use.
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