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LEMD2 Knockout Cell Lines

Gene: LEMD2

Official Full Name: LEM domain nuclear envelope protein 2provided by HGNC

Gene Summary: This gene encodes a LEM domain-containing transmembrane protein of the inner nuclear membrane. The protein is involved in nuclear structure organization and plays a role in cell signaling and differentiation. Mutations in this gene result in Cataract 46, juvenile-onset. Multiple transcript variants have been found for this gene. [provided by RefSeq, Feb 2017]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO27481 LEMD2 Knockout cell line (HeLa) Human LEMD2 1:3~1:6 Negative Online Inquiry
KO27482 LEMD2 Knockout cell line (HCT 116) Human LEMD2 1:2~1:4 Negative Online Inquiry
KO27483 LEMD2 Knockout cell line (HEK293) Human LEMD2 1:3~1:6 Negative Online Inquiry
KO27484 LEMD2 Knockout cell line (A549) Human LEMD2 1:3~1:4 Negative Online Inquiry

Background

LEMD2 Gene Knockout Cell Lines are genetically engineered cellular models that specifically lack the expression of the LEMD2 gene, which encodes a protein crucial for various cellular processes, including nuclear envelope integrity and gene regulation. These cell lines serve as powerful tools for researchers investigating not only the fundamental biology associated with LEMD2 but also its roles in numerous pathologies, such as cancer and genetic disorders.

Functionally, LEMD2 plays a significant role in the organization of the nuclear envelope and has been implicated in cellular signaling pathways. By utilizing LEMD2 Gene Knockout Cell Lines, scientists can effectively simulate the loss of LEMD2 function to elucidate its impact on cell cycle dynamics, cellular differentiation, and response to stress. These knockout models facilitate the investigation of molecular mechanisms underlying diseases, as well as the identification of potential therapeutic targets.

The scientific importance of LEMD2 Gene Knockout Cell Lines is underscored by their applicability in various research fields, including gene therapy, cancer biology, and developmental biology. In clinical settings, these models provide valuable insights into the mechanisms of diseases related to dysregulated nuclear envelope proteins, thus aiding in the development of novel therapeutic strategies.

One of the unique advantages of our LEMD2 Gene Knockout Cell Lines is their ready-to-use nature, accompanied by validated performance metrics in multiple experimental assays. Unlike conventional cell lines that require extensive time and resources for knockout validation, our product allows researchers to save time and accelerate their research timelines.

In summary, LEMD2 Gene Knockout Cell Lines represent an innovative product that adds significant value to the research community. As researchers and clinicians pursue new avenues in understanding complicated diseases, the precise, controlled environment offered by our knockout models can be a game-changer. With our commitment to high-quality biological products and robust support, we empower scientists to advance their research goals effectively.

Please note that all services are for research use only. Not intended for any clinical use.

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