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KRBA1 Knockout Cell Lines

Gene: KRBA1

Official Full Name: KRAB-A domain containing 1provided by HGNC

Gene Summary: Predicted to be involved in regulation of DNA-templated transcription. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO24767 KRBA1 Knockout cell line (HeLa) Human KRBA1 1:3~1:6 Negative Online Inquiry
KO24768 KRBA1 Knockout cell line (HEK293) Human KRBA1 1:3~1:6 Negative Online Inquiry
KO24769 KRBA1 Knockout cell line (A549) Human KRBA1 1:3~1:4 Negative Online Inquiry

Background

KRBA1 Gene Knockout Cell Lines represent a cutting-edge tool for genetic research and therapeutic development. These genetically modified cell lines are designed to specifically disrupt the KRBA1 gene, a critical regulator involved in various cellular processes, including apoptosis and cell proliferation. By utilizing CRISPR-Cas9 technology or similar gene-editing techniques, researchers can create precise knockout models that allow for the detailed study of gene function and its implications in disease states.

The primary function of KRBA1 gene knockout cell lines is to elucidate the role of the KRBA1 gene in biological processes and its contribution to disease mechanisms. When the KRBA1 gene is rendered non-functional, researchers can observe the consequential physiological changes and molecular pathways that are activated or suppressed, thus gaining valuable insights into cancer biology, neurodegeneration, and metabolic disorders. Through these knockout models, scientists can explore drug responses and the efficacy of potential therapeutic agents in a controlled environment, enhancing the relevance of their investigations to human health.

The scientific importance of KRBA1 gene knockout cell lines is substantial, as they can serve as a reliable platform for understanding gene function both in vitro and in vivo. Their applications range from basic research to clinical translation, including drug discovery, biomarker development, and contributing to advance personalized medicine. These cell lines are invaluable for researchers aiming to dissect complex gene interactions and pathways that characterize various conditions, including cancers where KRBA1 dysregulation plays a crucial role.

What sets KRBA1 gene knockout cell lines apart from alternative products is their specificity and reliability. While traditional knockdown approaches can result in variable expression due to incomplete silencing, knockout cell lines provide a definitive loss-of-function model that can yield unambiguous results. Additionally, these cell lines are readily accessible and can be easily integrated into existing research protocols, significantly reducing the time and effort required to generate new models.

For researchers and clinicians alike, the value of KRBA1 gene knockout cell lines lies in their ability to accelerate the understanding of disease mechanisms and provide a solid foundation for therapeutic innovations. By employing these advanced tools, the potential for scientific breakthroughs in understanding the role of KRBA1 in health and disease is greatly enhanced.

Our company is committed to providing high-quality biological research tools, and our expertise in gene-editing technology ensures that our KRBA1 gene knockout cell lines are designed to meet the rigorous standards of the scientific community. We are dedicated to supporting your research endeavors with our innovative products that pave the way for discoveries that can improve patient outcomes.

Please note that all services are for research use only. Not intended for any clinical use.

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