Gene: KIF20A
Official Full Name: kinesin family member 20Aprovided by HGNC
Gene Summary: Enables protein kinase binding activity. Involved in microtubule bundle formation; midbody abscission; and regulation of cytokinesis. Located in several cellular components, including intercellular bridge; midbody; and spindle. Implicated in restrictive cardiomyopathy. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO02782 | KIF20A Knockout cell line (HeLa) | Human | KIF20A | 1:3~1:6 | Negative | Online Inquiry |
KO02783 | KIF20A Knockout cell line (HCT 116) | Human | KIF20A | 1:2~1:4 | Negative | Online Inquiry |
KO02784 | KIF20A Knockout cell line (HEK293) | Human | KIF20A | 1:3~1:6 | Negative | Online Inquiry |
KO02785 | KIF20A Knockout cell line (A549) | Human | KIF20A | 1:3~1:4 | Negative | Online Inquiry |
KIF20A Gene Knockout Cell Lines are specially developed cellular models characterized by the targeted deletion of the KIF20A gene, which encodes for a motor protein involved in essential cellular processes, including cell division and intracellular transport. These cell lines serve as powerful tools for researchers aiming to elucidate the functional role of KIF20A in various physiological and pathological contexts.
The primary mechanism through which these knockout cell lines operate involves the absence of KIF20A, enabling investigators to study the cellular consequences of its loss, such as alterations in mitotic progression, cytokinesis defects, and aberrant cell proliferation. By comparing the knockout lines with their wild-type counterparts, researchers can gain significant insights into the molecular pathways that KIF20A influences, paving the way for a deeper understanding of diseases such as cancer, where KIF20A expression levels can be dysregulated.
The scientific importance of KIF20A Gene Knockout Cell Lines extends beyond basic research; they hold potential applications in drug discovery, target validation, and the development of therapeutic strategies. These models facilitate the examination of novel pharmacological agents aimed at modulating KIF20A-related pathways, making them invaluable for clinicians and researchers focused on translational medicine.
What sets KIF20A Gene Knockout Cell Lines apart from alternative models is their specificity and precision in gene editing, achieved using state-of-the-art CRISPR/Cas9 technology. This ensures a reliable and reproducible phenotype associated with the loss of KIF20A, allowing for consistent experimental outcomes. Additionally, the availability of these cell lines as validated products significantly reduces the time and resources often required for developing and characterizing new models.
For researchers, clinicians, and pharmaceutical developers, these cell lines represent a bridge between fundamental discovery and clinical application, offering a robust framework for investigation and innovation. Backed by a team of experts in genetic engineering and cell biology, our company is dedicated to providing high-quality biological products tailored to advance research endeavors and therapeutic advancements in the biomedical field.
Please note that all services are for research use only. Not intended for any clinical use.
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