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KDM5D Knockout Cell Lines

Gene: KDM5D

Official Full Name: lysine demethylase 5Dprovided by HGNC

Gene Summary: This gene encodes a protein containing zinc finger domains. A short peptide derived from this protein is a minor histocompatibility antigen which can lead to graft rejection of male donor cells in a female recipient. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO03357 KDM5D Knockout cell line (HCT 116) Human KDM5D 1:2~1:4 Negative Online Inquiry
KO03358 KDM5D Knockout cell line (A549) Human KDM5D 1:3~1:4 Negative Online Inquiry

Background

KDM5D Gene Knockout Cell Lines are genetically engineered cell lines that feature targeted deletions of the KDM5D gene, which encodes a histone demethylase involved in chromatin remodeling and gene expression regulation. By eliminating this specific gene, these cell lines serve as crucial tools for studying the role of KDM5D in cellular processes such as differentiation, proliferation, and cancer progression.

The primary function of KDM5D is to demethylate lysine 4 of histone H3, which plays a pivotal role in the epigenetic regulation of gene expression. The inactivation of this gene allows researchers to observe the resultant phenotypic changes, elucidating KDM5D’s involvement in various biological pathways. This gene knockout approach enables the exploration of gene function, the identification of downstream targets, and the potential uncovering of novel regulatory mechanisms impacting cellular homeostasis.

The significance of KDM5D Gene Knockout Cell Lines extends into both research and clinical applications. They provide invaluable insights into the epigenetic landscape of diseases, including various forms of cancer and developmental disorders. Researchers can utilize these cell lines for drug screening processes or therapeutic investigations, contributing to the understanding of disease mechanisms and informing novel treatment strategies.

One of the distinctive advantages of our KDM5D Gene Knockout Cell Lines is their high specificity and reproducibility compared to alternative models. While other knockout organisms or models may exhibit off-target effects or genetic variability, our cell lines are designed to provide consistent and reliable results, minimizing experimental variability and enhancing the accuracy of research outcomes.

In essence, KDM5D Gene Knockout Cell Lines offer researchers and clinicians a powerful tool in the quest for understanding the complexities of gene regulation and its implications for health and disease. Our company brings years of expertise in genetic engineering and cell line development, ensuring that our products meet the highest standards in scientific rigor and reliability, making them an essential addition to any laboratory focused on cutting-edge epigenetic research.

Please note that all services are for research use only. Not intended for any clinical use.

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