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KCTD5 Knockout Cell Lines

Gene: KCTD5

Official Full Name: potassium channel tetramerization domain containing 5provided by HGNC

Gene Summary: Enables identical protein binding activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Located in cytosol. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO21765 KCTD5 Knockout cell line (HeLa) Human KCTD5 1:3~1:6 Negative Online Inquiry
KO21766 KCTD5 Knockout cell line (HCT 116) Human KCTD5 1:2~1:4 Negative Online Inquiry
KO21767 KCTD5 Knockout cell line (HEK293) Human KCTD5 1:3~1:6 Negative Online Inquiry
KO21768 KCTD5 Knockout cell line (A549) Human KCTD5 1:3~1:4 Negative Online Inquiry

Background

KCTD5 Gene Knockout Cell Lines are engineered cellular models that have undergone targeted gene disruption of the KCTD5 gene, which is known to play a significant role in neuronal function and synaptic processes. By employing CRISPR/Cas9 or other advanced gene-editing technologies, these cell lines provide invaluable tools for studying the downstream effects of KCTD5 absence on cellular pathways, protein interactions, and phenotypic alterations, thereby enabling a deeper understanding of its biological roles.

The primary function of KCTD5 is associated with modulating the activity of various ion channels and receptors, impacting cellular excitability and signaling cascades. The knockout of this gene allows researchers to observe changes in neurotransmitter release, synaptic plasticity, and the potential implications in neurodevelopmental disorders, providing insights that are crucial for advancing therapeutic strategies.

In both research and clinical settings, these cell lines serve as pivotal resources for drug discovery, biomarker validation, and the exploration of disease mechanisms related to KCTD5 dysregulation. The scientific importance lies in their ability to bridge the gap between in vitro studies and potential in vivo applications, allowing for more accurate modeling of disease conditions.

One of the distinct advantages of the KCTD5 Gene Knockout Cell Lines compared to other existing models is their specificity and the reliability of the knockout approach, which directly enables the study of KCTD5's functional contributions without the confounding effects typically encountered in experimental models. This precision minimizes variability and enhances the reproducibility of research findings.

For researchers and clinicians seeking to elucidate the complexities of neuronal mechanisms or to develop targeted interventions, these cell lines represent a significant asset. They provide a streamlined pathway for experimentation while ensuring scientific rigor, ultimately fostering innovation in understanding and treating neurological conditions.

Our company specializes in delivering high-quality biological products, including expertly validated gene knockout models, ensuring that our customers have the tools necessary for advancing their research objectives effectively.

Please note that all services are for research use only. Not intended for any clinical use.

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