Gene: JAGN1
Official Full Name: jagunal homolog 1provided by HGNC
Gene Summary: The protein encoded by this gene is a transmembrane protein. It functions in the early secretory pathway and is necessary for neutrophil differentiation and survival. Mutations in this gene result in severe congenital neutropenia. [provided by RefSeq, Oct 2014]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO24823 | JAGN1 Knockout cell line (HeLa) | Human | JAGN1 | 1:3~1:6 | Negative | Online Inquiry |
KO24824 | JAGN1 Knockout cell line (HCT 116) | Human | JAGN1 | 1:2~1:4 | Negative | Online Inquiry |
KO24825 | JAGN1 Knockout cell line (HEK293) | Human | JAGN1 | 1:3~1:6 | Negative | Online Inquiry |
KO24826 | JAGN1 Knockout cell line (A549) | Human | JAGN1 | 1:3~1:4 | Negative | Online Inquiry |
JAGN1 Gene Knockout Cell Lines are sophisticated cellular models designed to facilitate the study of the Jagunal 1 (JAGN1) gene's roles in cellular biology. This gene, crucial for various physiological processes, is implicated in protein quality control, immune response, and cellular metabolism. Our knockout cell lines exhibit a complete elimination of JAGN1 expression, enabling researchers to analyze the resulting phenotypic effects and investigate the underlying molecular pathways.
These cell lines function as invaluable tools for understanding how the absence of JAGN1 influences cell proliferation, differentiation, and response to stressors. By utilizing CRISPR-Cas9 gene editing technology, the knockout process is both precise and efficient, ensuring consistent reproducibility across experiments. Researchers can delve into the implications of JAGN1 loss in various contexts, such as autoimmune diseases or cancer, leading to discoveries that may inform therapeutic interventions.
The scientific importance of these cell lines extends to drug discovery and development, where elucidating the mechanistic pathways associated with JAGN1 can unveil new biomarkers or treatment targets. Moreover, researchers can leverage these cell lines to study the effects of potential small molecule inhibitors or gene therapies, thus contributing to advancements in personalized medicine.
Compared to traditional methodologically cumbersome approaches, our JAGN1 Gene Knockout Cell Lines offer a streamlined and user-friendly solution, significantly reducing experimental time while enhancing data reliability. This contributes to greater research productivity and accelerates the pace at which new insights are gained.
For researchers, clinicians, and biotechnologists, the ability to interrogate gene function with precision is paramount in forwarding scientific knowledge and clinical application. With our commitment to innovation and quality, our company stands at the forefront of biological product development, offering unparalleled expertise and an extensive portfolio to support the research community in tackling complex biological questions.
Please note that all services are for research use only. Not intended for any clinical use.
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