Gene: JADE3
Official Full Name: jade family PHD finger 3provided by HGNC
Gene Summary: This gene encodes a member of a family of large proteins containing PHD (plant homeo domain)-type zinc fingers. The encoded protein may be associated in a nuclear complex that functions in histone H4 acetylation. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Aug 2013]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO32798 | JADE3 Knockout cell line (HeLa) | Human | JADE3 | 1:3~1:6 | Negative | Online Inquiry |
KO32799 | JADE3 Knockout cell line (HCT 116) | Human | JADE3 | 1:2~1:4 | Negative | Online Inquiry |
KO32800 | JADE3 Knockout cell line (HEK293) | Human | JADE3 | 1:3~1:6 | Negative | Online Inquiry |
KO32801 | JADE3 Knockout cell line (A549) | Human | JADE3 | 1:3~1:4 | Negative | Online Inquiry |
JADE3 Gene Knockout Cell Lines are meticulously developed cellular models designed to facilitate in-depth studies of gene function and regulation, particularly focusing on the JADE3 gene. This innovative product utilizes CRISPR-Cas9 gene-editing technology to create stable knockout cell lines, thereby enabling researchers to analyze the biological consequences of JADE3 gene loss across various cellular processes. By inhibiting this specific gene, the cell lines provide valuable insights into mechanisms of gene expression, signal transduction pathways, and overall cellular behavior, making them vital tools for both basic and applied research.
In terms of functionality, these cell lines are engineered to exhibit a complete loss of JADE3 expression, allowing for the examination of resultant phenotypic changes, including alterations in proliferation, apoptosis, and differentiation. The mechanisms by which JADE3 is implicated in cellular activities can be traced through various assays, providing clarity on its role in fundamental biological processes and disease pathogenesis. Such investigations are crucial in therapeutic research, including cancer biology, where JADE3's regulatory effects could unveil new targets for intervention.
The scientific importance of JADE3 Gene Knockout Cell Lines extends into clinical settings, particularly in the development of novel therapeutics. By providing a robust platform for drug testing and biomarker discovery, these cell lines can significantly streamline translational research efforts. Compared to other gene knockout models, the unparalleled specificity and efficiency of CRISPR-Cas9 technology used in these cell lines offer distinct advantages, including reduced off-target effects and enhanced reproducibility across experiments.
For researchers and clinicians striving for accuracy and innovation in their studies, JADE3 Gene Knockout Cell Lines present an invaluable resource. They not only simplify the exploration of gene functionality but also serve as a bridge toward potential clinical applications, including personalized medicine strategies. Our company, renowned for its commitment to advancing genetic research through high-quality biological products, ensures that each cell line is rigorously tested for quality and performance, underscoring our expertise in genetic engineering and cellular biology. By choosing JADE3, you equip your research with a powerful tool to uncover the complexities of gene regulation and its implications in health and disease.
Please note that all services are for research use only. Not intended for any clinical use.
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