Gene: JADE1
Official Full Name: jade family PHD finger 1provided by HGNC
Gene Summary: Enables transcription coactivator activity. Contributes to histone acetyltransferase activity. Involved in several processes, including negative regulation of canonical Wnt signaling pathway; regulation of cell growth; and regulation of nucleobase-containing compound metabolic process. Acts upstream of or within negative regulation of G1/S transition of mitotic cell cycle. Located in several cellular components, including cytosol; microtubule organizing center; and nuclear speck. Part of histone acetyltransferase complex. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO16862 | JADE1 Knockout cell line (HeLa) | Human | JADE1 | 1:3~1:6 | Negative | Online Inquiry |
KO16863 | JADE1 Knockout cell line (HCT 116) | Human | JADE1 | 1:2~1:4 | Negative | Online Inquiry |
KO16864 | JADE1 Knockout cell line (HEK293) | Human | JADE1 | 1:3~1:6 | Negative | Online Inquiry |
KO16865 | JADE1 Knockout cell line (A549) | Human | JADE1 | 1:3~1:4 | Negative | Online Inquiry |
JADE1 Gene Knockout Cell Lines are genetically engineered cell lines designed to provide researchers with a powerful tool for studying the biological functions of the JADE1 gene. This gene plays a crucial role in chromatin remodeling and gene expression regulation, with implications in various cellular processes including cell proliferation and differentiation. By utilizing CRISPR-Cas9 technology, these knockout cell lines effectively disrupt the JADE1 locus, allowing for the investigation of its functional significance in various models of disease.
The primary mechanism of action for the JADE1 knockout cell lines is the targeted deletion of the JADE1 gene, which leads to a phenotypic alteration that can be examined under different experimental conditions. Researchers can study the consequent changes in cell behavior, signaling pathways, and gene expression patterns, providing valuable insights into the role of JADE1 in health and disease.
The scientific importance of JADE1 knockout cell lines extends across multiple research domains, including oncology, developmental biology, and regenerative medicine. In clinical settings, these cell lines can be employed to identify potential therapeutic targets and to elucidate the mechanisms underlying certain diseases, such as cancer or genetic disorders related to epigenetic regulation.
What sets our JADE1 Gene Knockout Cell Lines apart from alternatives on the market is their high specificity and consistency, ensuring reproducible results across experiments. Coupled with a robust quality assurance framework, our cell lines are validated for key characteristics that support rigorous scientific inquiries.
For researchers and clinicians alike, the ability to manipulate the JADE1 gene provides an invaluable opportunity to further dissect complex biological pathways and identify novel intervention points. The profound implications of gaining a deeper understanding of gene function emphasize the significance of integrating JADE1 knockout cell lines into your research arsenal.
Our company prides itself on a long-standing commitment to advancing the field of genetic research. With a portfolio of high-quality biological products and continuous innovation, we are dedicated to supporting the scientific community in unlocking the mysteries of gene function and translating this knowledge into meaningful therapeutic advancements.
Please note that all services are for research use only. Not intended for any clinical use.
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