Gene: HMMR
Official Full Name: hyaluronan mediated motility receptorprovided by HGNC
Gene Summary: The protein encoded by this gene is involved in cell motility. It is expressed in breast tissue and together with other proteins, it forms a complex with BRCA1 and BRCA2, thus is potentially associated with higher risk of breast cancer. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Dec 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO04165 | HMMR Knockout cell line (HeLa) | Human | HMMR | 1:3~1:6 | Negative | Online Inquiry |
KO04166 | HMMR Knockout cell line (HCT 116) | Human | HMMR | 1:2~1:4 | Negative | Online Inquiry |
KO04167 | HMMR Knockout cell line (HEK293) | Human | HMMR | 1:3~1:6 | Negative | Online Inquiry |
KO04168 | HMMR Knockout cell line (A549) | Human | HMMR | 1:3~1:4 | Negative | Online Inquiry |
HMMR Gene Knockout Cell Lines are genetically engineered cell models specifically designed to lack the expression of the HMMR gene, a critical component involved in cell migration, adhesion, and proliferation. These knockout lines enable scientists to investigate the functional roles of HMMR in various biological contexts, ranging from cancer progression to developmental biology. By employing CRISPR-Cas9 technology, the HMMR gene is precisely targeted and disrupted, allowing for insights into the downstream signaling pathways affected by its absence.
The primary function of HMMR (Hyaluronan Mediated Motility Receptor) is to facilitate cellular interactions with the extracellular matrix, which plays a crucial role in tissue morphogenesis and cell plasticity. By utilizing HMMR Gene Knockout Cell Lines, researchers can delineate how the loss of HMMR impacts cellular behaviors, such as invasion and metastasis—key processes in tumor biology. Furthermore, these cell lines serve as valuable tools for drug screening and therapeutic development, particularly in identifying potential compounds that target adhesion and migratory pathways.
The scientific significance of HMMR Gene Knockout Cell Lines extends to multiple applications in both basic and applied research. Clinicians and researchers can leverage these models to better understand the etiology of diseases where HMMR is implicated, such as various cancers and fibrotic conditions. Compared to alternative cell models, our HMMR knockouts are rigorously validated for functional consistency and genetic fidelity, ensuring reliable experimental outcomes.
One of the standout advantages of utilizing these cell lines lies in their versatility and adaptability to a broad spectrum of research methodologies, including high-throughput screening and co-culture systems. By choosing HMMR Gene Knockout Cell Lines, users have the unique opportunity to unravel complex biological interactions and contribute to transformative discoveries in the medical and scientific community.
Our company prides itself on delivering high-quality, robust biological products, backed by extensive research and expertise in cell line development. We are committed to supporting the scientific community by providing reliable tools that advance research and enhance therapeutic strategies, making us a trusted partner for researchers and clinicians alike.
Please note that all services are for research use only. Not intended for any clinical use.
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