Gene: GTPBP1
Official Full Name: GTP binding protein 1provided by HGNC
Gene Summary: This gene is upregulated by interferon-gamma and encodes a protein that is a member of the AGP11/GTPBP1 family of GTP-binding proteins. A structurally similar protein has been found in mouse, where disruption of the gene for that protein had no observable phenotype. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO33092 | GTPBP1 Knockout cell line (HeLa) | Human | GTPBP1 | 1:3~1:6 | Negative | Online Inquiry |
KO33093 | GTPBP1 Knockout cell line (HCT 116) | Human | GTPBP1 | 1:2~1:4 | Negative | Online Inquiry |
KO33094 | GTPBP1 Knockout cell line (HEK293) | Human | GTPBP1 | 1:3~1:6 | Negative | Online Inquiry |
KO33095 | GTPBP1 Knockout cell line (A549) | Human | GTPBP1 | 1:3~1:4 | Negative | Online Inquiry |
GTPBP1 Gene Knockout Cell Lines are genetically modified cell lines in which the GTPBP1 gene has been systematically disrupted to elucidate its biological functions and implications in cellular processes. GTPBP1, or GTP-binding protein 1, is integral in various cellular signaling pathways, particularly those involving translation and ribosome biogenesis, making its study crucial for understanding the mechanistic underpinnings of cellular growth and differentiation.
The primary mechanism of action for these knockout cell lines involves homologous recombination, where the native GTPBP1 gene is replaced or disabled to prevent normal protein production. This allows researchers to observe phenotypic changes and alterations in signaling pathways that occur in the absence of the gene. Notably, these cell lines can offer insights into potential therapeutic targets for diseases associated with dysregulated GTPBP1 activity, such as certain cancers.
From a scientific perspective, GTPBP1 Gene Knockout Cell Lines serve as valuable tools in both research and clinical settings. They enable high-throughput screening for drug discovery, facilitate the identification of genetic interactions, and provide a platform for studying gene function in the context of disease models. Their applications extend to exploring mechanisms of RNA metabolism and the regulation of protein synthesis.
What sets GTPBP1 Gene Knockout Cell Lines apart from alternative models is their specificity and the high fidelity of gene editing techniques employed for their development. Compared to more conventional models, these cell lines offer a closer approximation to in vivo conditions, reducing the variability typically associated with transgenic systems.
For researchers and clinicians aiming to delve deeper into the molecular intricacies of gene function and develop novel therapies, these cell lines present an invaluable resource. By employing GTPBP1 Gene Knockout Cell Lines, users can leverage robust experimental methodologies to drive innovation in therapeutic development and mechanistic discovery.
Our company prides itself on delivering meticulously validated biological products designed to enhance research efficacy and expand scientific horizons. With unmatched expertise in gene editing technologies, we are committed to supporting the scientific community with high-quality tools that advance our understanding of complex biological systems.
Please note that all services are for research use only. Not intended for any clinical use.
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