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GPX7 Knockout Cell Lines

Gene: GPX7

Official Full Name: glutathione peroxidase 7provided by HGNC

Gene Summary: Enables catalase activity. Predicted to be involved in cellular response to oxidative stress. Located in endoplasmic reticulum. Implicated in Barrett's adenocarcinoma and Barrett's esophagus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO37505 GPX7 Knockout cell line (HeLa) Human GPX7 1:3~1:6 Negative Online Inquiry

Background

GPX7 Gene Knockout Cell Lines are specifically engineered cellular models designed to study the functional roles of the GPX7 gene, which encodes a member of the glutathione peroxidase family. This enzyme is integral to cellular antioxidant defense mechanisms, responsible for reducing peroxides and protecting cells from oxidative stress. By knocking out the GPX7 gene, these cell lines provide a unique platform for investigating the consequences of GPX7 deficiency, enabling researchers to elucidate its role in cellular proliferation, apoptosis, and response to oxidative stress.

The primary function of GPX7 is to catalyze the reduction of hydrogen peroxide and organic hydroperoxides, thereby mitigating cellular damage induced by oxidative agents. These knockout cell lines facilitate an in-depth analysis of the biochemical pathways altered in the absence of GPX7, including implications for cancer progression, neurodegenerative diseases, and other conditions where oxidative stress plays a pivotal role. They serve as invaluable tools in academic and pharmaceutical research, offering insights into the molecular mechanisms underpinning these pathologies.

Compared to traditional wild-type cell lines, GPX7 Gene Knockout Cell Lines present a significant advantage by enabling the investigation of gene-specific functions without the compensatory mechanisms that often confound results in wild-type models. Their design allows researchers to achieve accurate data on gene function with higher specificity and reproducibility.

For researchers and clinicians focused on oxidation-related studies or therapeutic interventions targeting oxidative stress pathways, GPX7 Gene Knockout Cell Lines represent an essential resource. The ability to explore various biological phenomena in a controlled genetic context ultimately accelerates research endeavors and improves the development of targeted treatments.

Our company prides itself on advancing scientific knowledge by providing high-quality biological products like the GPX7 Gene Knockout Cell Lines, ensuring researchers have access to reliable tools that facilitate groundbreaking discoveries. With a commitment to innovation and quality, we support the scientific community in addressing complex biological questions with clarity and precision.

Please note that all services are for research use only. Not intended for any clinical use.

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