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GNPDA2 Knockout Cell Lines

Gene: GNPDA2

Official Full Name: glucosamine-6-phosphate deaminase 2provided by HGNC

Gene Summary: The protein encoded by this gene is an allosteric enzyme that catalyzes the reversible reaction converting D-glucosamine-6-phosphate into D-fructose-6-phosphate and ammonium. Variations of this gene have been reported to be associated with influencing body mass index and susceptibility to obesity. A pseudogene of this gene is located on chromosome 9. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Aug 2012]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO26507 GNPDA2 Knockout cell line (HeLa) Human GNPDA2 1:3~1:6 Negative Online Inquiry
KO26508 GNPDA2 Knockout cell line (HCT 116) Human GNPDA2 1:2~1:4 Negative Online Inquiry
KO26509 GNPDA2 Knockout cell line (HEK293) Human GNPDA2 1:3~1:6 Negative Online Inquiry
KO26510 GNPDA2 Knockout cell line (A549) Human GNPDA2 1:3~1:4 Negative Online Inquiry

Background

GNPDA2 Gene Knockout Cell Lines are genetically modified cell lines where the GNPDA2 gene has been disrupted to facilitate the study of its biological functions and implications in various physiological and pathological processes. GNPDA2, or glucosamine-6-phosphate deaminase 2, is a critical enzyme involved in amino sugar metabolism, and its knockout enables researchers to analyze the pathways influenced by its absence and the resulting metabolic changes.

The key functions of these cell lines are rooted in their ability to provide a controlled environment for assessing the role of GNPDA2 in cellular metabolism, signaling pathways, and disease states, particularly in metabolic disorders and cancers. By utilizing these knockout models, researchers can dissect the mechanistic pathways that contribute to obesity and diabetes, offering insights into how alterations in amino sugar metabolism may affect overall cellular function and disease progression.

The scientific importance of GNPDA2 Gene Knockout Cell Lines lies in their application in both fundamental research and clinical settings. These models serve as invaluable tools for drug development and screening, enabling the identification of potential therapeutic targets. They allow for the exploration of gene interactions and the impact of metabolic dysregulation in disease contexts, facilitating breakthroughs in understanding complex biological systems.

What sets our GNPDA2 Gene Knockout Cell Lines apart from alternatives is the precision of our gene editing technology, which ensures high specificity and minimal off-target effects. Additionally, our lines are validated through rigorous testing, ensuring consistent and reliable results for your experiments.

For researchers, clinicians, and biotech companies, the ability to utilize these specialized cell lines provides a unique advantage in advancing scientific knowledge and therapeutic strategies. Investing in these knockout cell lines can significantly enhance research capabilities by simplifying experimental designs and yielding reproducible data that drive innovation.

With a commitment to excellence, our company specializes in producing high-quality biological products backed by advanced genetic engineering techniques, empowering the scientific community to push the boundaries of research and clinical practice.

Please note that all services are for research use only. Not intended for any clinical use.

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