Gene: GIGYF2
Official Full Name: GRB10 interacting GYF protein 2provided by HGNC
Gene Summary: This gene contains CAG trinucleotide repeats and encodes a protein containing several stretches of polyglutamine residues. The encoded protein may be involved in the regulation of tyrosine kinase receptor signaling. This gene is located in a chromosomal region that was genetically linked to Parkinson disease type 11, and mutations in this gene were thought to be causative for this disease. However, more recent studies in different populations have been unable to replicate this association. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO28416 | GIGYF2 Knockout cell line (HeLa) | Human | GIGYF2 | 1:3~1:6 | Negative | Online Inquiry |
KO28417 | GIGYF2 Knockout cell line (HCT 116) | Human | GIGYF2 | 1:2~1:4 | Negative | Online Inquiry |
KO28418 | GIGYF2 Knockout cell line (HEK293) | Human | GIGYF2 | 1:3~1:6 | Negative | Online Inquiry |
KO28419 | GIGYF2 Knockout cell line (A549) | Human | GIGYF2 | 1:3~1:4 | Negative | Online Inquiry |
GIGYF2 Gene Knockout Cell Lines are specialized cellular models that have been genetically modified to lack functional expression of the GIGYF2 gene, which encodes for the growth regulatory protein involved in various cellular processes, including translation regulation and cellular growth pathways. These cell lines serve as invaluable tools for studying the role of GIGYF2 in biological functions and disease mechanisms, particularly in cancer research and neurological studies.
The key function of GIGYF2 Gene Knockout Cell Lines lies in their ability to mimic the loss-of-function scenarios that researchers need to explore specific pathways and interactions. By utilizing CRISPR-Cas9 technology, these cell lines ensure precise gene editing, leading to reliable and reproducible phenotypes essential for investigating the repercussions of GIGYF2 deficiency on cell proliferation, differentiation, and apoptosis.
Scientifically, these knockout cell lines are instrumental in advancing our understanding of the oncogenic and neurodegenerative pathways associated with GIGYF2, offering insights for potential therapeutic interventions. They provide a reliable platform for drug testing, genomic studies, and functional assays, driving innovations in both research and clinical applications.
Compared to alternative models such as transient knockdowns or wild-type cells, GIGYF2 Gene Knockout Cell Lines offer a stable and consistent genetic background, significantly enhancing the accuracy of experimental outcomes. Their unique ability to maintain a knockout phenotype over extended passages ensures quality and reliability, reducing the variability commonly seen with transient expression systems.
For researchers investigating the complexities of gene regulation and the implications of GIGYF2 in health and disease, these cell lines represent a significant value addition. They empower users to conduct in-depth analyses, leading to a more profound understanding of critical biological processes and therapeutic target identification.
Our company specializes in advanced genetic tools, providing state-of-the-art biological products that facilitate groundbreaking research. With a robust track record in gene editing technology and a commitment to supporting the scientific community, we are dedicated to delivering high-quality, reliable products that drive innovations in life sciences.
Please note that all services are for research use only. Not intended for any clinical use.
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