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GALK2 Knockout Cell Lines

Gene: GALK2

Official Full Name: galactokinase 2provided by HGNC

Gene Summary: This gene encodes a highly efficient N-acetylgalactosamine (GalNAc) kinase, which has galactokinase activity when galactose is present at high concentrations. The encoded protein is a member of the GHMP kinase family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2017]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO37721 GALK2 Knockout cell line (HeLa) Human GALK2 1:3~1:6 Negative Online Inquiry
KO37722 GALK2 Knockout cell line (HCT 116) Human GALK2 1:2~1:4 Negative Online Inquiry
KO37723 GALK2 Knockout cell line (HEK293) Human GALK2 1:3~1:6 Negative Online Inquiry
KO37724 GALK2 Knockout cell line (A549) Human GALK2 1:3~1:4 Negative Online Inquiry

Background

GALK2 Gene Knockout Cell Lines are a sophisticated biological tool designed to facilitate the study of galactokinase (GALK) 2 genes, which play a critical role in galactose metabolism. These cell lines have been genetically engineered to exhibit a complete knockout of the GALK2 gene, enabling researchers to investigate the gene's function and the metabolic pathways it influences. By eliminating GALK2, these cell lines allow for a more controlled environment to observe the effects of galactose and related metabolic alterations on cellular processes, providing insights into conditions such as galactosemia and its cellular implications.

The primary mechanism through which GALK2 Knockout Cell Lines operate is by disrupting the normal enzymatic activity associated with galactose metabolism. Researchers can directly assess the consequences of this disruption on various cellular processes, including energy production, cell growth, and apoptosis, thus illuminating the importance of GALK2 in cellular physiology. The absence of this gene creates a unique model for studying the metabolic dysregulation that can occur due to disruptions in galactose handling.

From a scientific perspective, these cell lines hold significant value in both research and clinical applications. They serve as vital models for drug discovery and testing, with potential implications for treating metabolic disorders. Additionally, GALK2 knockout models can enhance our understanding of broader metabolic syndromes that transcend individual enzyme function.

What sets our GALK2 Gene Knockout Cell Lines apart from other genetic models is their high specificity and efficacy, ensuring that researchers achieve reproducible results necessary for rigorous scientific inquiry. Furthermore, they are developed with the latest gene-editing technologies, ensuring the precision and consistency required for effective experimentation.

For researchers and clinicians, investing in GALK2 Gene Knockout Cell Lines is not merely a choice; it's an essential strategic tool that unlocks new pathways for understanding galactose metabolism and its associated disorders. With your research and mode of inquiry as a priority, our company's expertise in advanced genetic editing techniques underpins our commitment to providing cutting-edge biological products tailored for your needs.

Please note that all services are for research use only. Not intended for any clinical use.

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