Gene: Foxk2
Official Full Name: forkhead box K2provided by MGI
Gene Summary: Enables DNA-binding transcription repressor activity, RNA polymerase II-specific. Involved in several processes, including intracellular glucose homeostasis; negative regulation of autophagy; and regulation of DNA-templated transcription. Located in cytoplasm and nucleus. Is expressed in several structures, including blastocyst; nervous system; reproductive system; and urinary system. Orthologous to human FOXK2 (forkhead box K2). [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO01220 | Foxk2 Knockout cell line(Lbetat2) | Mouse | Foxk2 | 1:2-1:4 | Negative | Online Inquiry |
Foxk2 Gene Knockout Cell Lines are genetically engineered cell lines in which the Foxk2 gene has been completely inactivated. The Foxk2 gene encodes a transcription factor that plays a pivotal role in various cellular processes, including cell cycle regulation, differentiation, and apoptosis. By employing CRISPR-Cas9 technology for precise gene editing, these cell lines serve as a critical tool for researchers investigating the biological functions of the Foxk2 gene and its implications in different pathological contexts.
These cell lines operate by eliminating the expression of the Foxk2 protein, allowing scientists to study the resultant phenotypic changes and molecular pathways affected by its absence. This mechanism facilitates a deeper understanding of Foxk2's role in diseases such as cancer, where its regulation can influence tumor progression and cellular responses to therapy. In addition to basic research, the Foxk2 Gene Knockout Cell Lines are invaluable in drug discovery and development, as they provide a model for evaluating therapeutic responses and identifying potential target interactions.
The scientific importance of these cell lines extends into clinical research, where elucidating the role of Foxk2 can reveal novel biomarkers or therapeutic targets for various diseases. The unique advantage of Foxk2 Gene Knockout Cell Lines lies in their specific targeting, which allows for reliable and reproducible results when compared to alternative methods like RNA interference that may not completely abolish gene expression.
For researchers and clinicians, the value of utilizing Foxk2 Gene Knockout Cell Lines is clear; they offer a robust and precise model to dissect the complexities of gene function and regulation. These cell lines ensure a thorough exploration of the Foxk2 pathway, ultimately supporting advancements in both fundamental and applied biological research.
Our company, dedicated to providing high-quality biological products, leverages extensive expertise in genetic engineering and cell line development to deliver innovative solutions that accelerate research and improve clinical outcomes.
Please note that all services are for research use only. Not intended for any clinical use.
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