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FOXL2NB Knockout Cell Lines

Gene: FOXL2NB

Official Full Name: FOXL2 neighborprovided by HGNC

Gene Summary: Located in fibrillar center. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO21387 FOXL2NB Knockout cell line (HeLa) Human FOXL2NB 1:3~1:6 Negative Online Inquiry
KO21388 FOXL2NB Knockout cell line (A549) Human FOXL2NB 1:3~1:4 Negative Online Inquiry

Background

FOXL2NB Gene Knockout Cell Lines are specialized cell culture systems engineered to lack the FOXL2NB gene, a critical regulator involved in folliculogenesis and reproductive processes. This bespoke model serves as a powerful tool for researchers aiming to dissect the molecular functions associated with this gene and its implications in developmental biology and reproductive health. The knockout mechanism is achieved through CRISPR-Cas9 technology, ensuring precise editing that eliminates the expression of FOXL2NB, allowing researchers to directly observe the resulting phenotypic changes and molecular pathways affected by this gene's absence.

The key function of these knockout cell lines lies in their ability to elucidate the role of FOXL2NB in various biological processes, including cell growth, differentiation, and hormonal responses. They are particularly valuable in studies related to ovarian function and development, offering insights into conditions such as premature ovarian failure or ovarian cancer. The ability to manipulate and analyze these cells provides substantial leaps in understanding both normal physiology and disease state mechanisms.

In research and clinical settings, the scientific importance of FOXL2NB knockout models cannot be overstated; they are crucial for developing targeted therapies and improving diagnostics related to reproductive health. These models can also facilitate drug screening and toxicity studies, enhancing the efficiency of preclinical research.

Compared to conventional models, such as wild-type cell lines or animal models, FOXL2NB Gene Knockout Cell Lines present unique advantages, including reduced variability and ethical considerations associated with animal use. Their precise genomic editing offers higher reproducibility and enables straightforward comparison across experimental setups.

For researchers and clinicians focused on reproductive biology, these knockout cell lines represent a transformative tool that enhances the understanding of complex gene interactions and their impact on human health. Our company brings years of expertise in the field of genetic engineering and cell line development, ensuring that you can trust the quality and reliability of our products. By choosing our FOXL2NB Gene Knockout Cell Lines, you are equipping yourself with an invaluable resource to advance your research endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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