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FITM2 Knockout Cell Lines

Gene: FITM2

Official Full Name: fat storage inducing transmembrane protein 2provided by HGNC

Gene Summary: Enables coenzyme A diphosphatase activity. Involved in several processes, including fatty-acyl-CoA catabolic process; lipid droplet formation; and lipid homeostasis. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be active in endoplasmic reticulum membrane. Implicated in Siddiqi syndrome. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO26761 FITM2 Knockout cell line (HeLa) Human FITM2 1:3~1:6 Negative Online Inquiry
KO26762 FITM2 Knockout cell line (HCT 116) Human FITM2 1:2~1:4 Negative Online Inquiry
KO26763 FITM2 Knockout cell line (HEK293) Human FITM2 1:3~1:6 Negative Online Inquiry
KO26764 FITM2 Knockout cell line (A549) Human FITM2 1:3~1:4 Negative Online Inquiry

Background

FITM2 Gene Knockout Cell Lines represent a groundbreaking advancement in cellular biology, specifically engineered to study the function and regulatory mechanisms of the FITM2 gene, which is implicated in lipid metabolism and cellular signaling pathways. These cell lines have undergone precise CRISPR-Cas9 gene editing, resulting in a complete knockout of FITM2 expression, allowing researchers to elucidate the gene's role in physiological and pathological contexts with high specificity.

The primary function of FITM2 involves the modulation of lipid droplet formation and storage, crucial for energy homeostasis and cellular metabolism. By utilizing these knockout cell lines, scientists can investigate the downstream effects of FITM2 loss, including alterations in lipid profiles, cellular stress responses, and potential impacts on metabolic disorders such as obesity or diabetes. This experimental model also supports the exploration of therapeutic targets for drug development aimed at metabolic diseases.

One of the significant advantages of FITM2 Gene Knockout Cell Lines is their robustness in replicating the phenotypic consequences of gene deletion, providing a clearer understanding compared to traditional methods that may involve transient knockdown. Unlike commercially available alternatives, these cell lines are extensively validated, ensuring reproducibility and reliability in experimental results.

For researchers and clinicians focused on metabolic research, the FITM2 Gene Knockout Cell Lines offer unparalleled insights into gene function, enabling the design of targeted therapies and improving the understanding of metabolic diseases. Moreover, our commitment to quality and innovation positions us as a leader in developing advanced biological research tools, ensuring that our products meet the highest standards of scientific excellence.

Please note that all services are for research use only. Not intended for any clinical use.

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