Gene: FHOD1
Official Full Name: formin homology 2 domain containing 1provided by HGNC
Gene Summary: This gene encodes a protein which is a member of the formin/diaphanous family of proteins. The gene is ubiquitously expressed but is found in abundance in the spleen. The encoded protein has sequence homology to diaphanous and formin proteins within the Formin Homology (FH)1 and FH2 domains. It also contains a coiled-coil domain, a collagen-like domain, two nuclear localization signals, and several potential PKC and PKA phosphorylation sites. It is a predominantly cytoplasmic protein and is expressed in a variety of human cell lines. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO27142 | FHOD1 Knockout cell line (HeLa) | Human | FHOD1 | 1:3~1:6 | Negative | Online Inquiry |
KO27143 | FHOD1 Knockout cell line (HCT 116) | Human | FHOD1 | 1:2~1:4 | Negative | Online Inquiry |
KO27144 | FHOD1 Knockout cell line (HEK293) | Human | FHOD1 | 1:3~1:6 | Negative | Online Inquiry |
KO27145 | FHOD1 Knockout cell line (A549) | Human | FHOD1 | 1:3~1:4 | Negative | Online Inquiry |
FHOD1 Gene Knockout Cell Lines are specialized cellular models designed to elucidate the biological functions of the FHOD1 gene, which encodes a member of the formin family of proteins known to play crucial roles in actin dynamics and cell morphology. This product offers researchers a powerful tool to investigate how the loss of the FHOD1 gene impacts cellular processes such as migration, adhesion, and division. By specifically knocking out the FHOD1 gene, these cell lines enable the examination of the corresponding phenotypic changes in vitro, providing insights into the mechanisms underlying various cellular behaviors and signaling pathways.
The key functions of the FHOD1 Gene Knockout Cell Lines lie in their ability to model conditions of FHOD1 deficiency, facilitating the study of actin filament assembly and organization. These cell lines exhibit altered cytoskeletal architecture and dynamics, allowing for the analysis of how FHO1 contributes to cellular functions like motility and interaction with the extracellular matrix. Researchers can leverage these cell lines to explore the implications of FHOD1 loss in health and disease, particularly in contexts such as cancer progression and cardiovascular conditions.
The scientific importance of FHOD1 Gene Knockout Cell Lines is underscored by their applicability in both basic research and potential clinical settings. Understanding the role of FHOD1 can shed light on pathophysiological processes, opening avenues for therapeutic interventions. Beyond research, the insights gained from these cell models can translate to improved diagnostics or innovative treatment strategies in clinical practice.
What sets FHOD1 Gene Knockout Cell Lines apart from alternative models is their specificity and precision in targeting the FHOD1 gene, ensuring a robust and reproducible outcome for experiments. Additionally, these cell lines are derived from well-characterized origins, offering researchers confidence in their authenticity and relevance to human biology.
For researchers and clinicians alike, the FHOD1 Gene Knockout Cell Lines represent a significant advancement in the study of cellular mechanics and signal transduction. The value of these models extends beyond the laboratory; they empower scientists to pave the way for breakthroughs in our understanding of complex biological systems. At our company, we pride ourselves on offering high-quality, innovative biological products, underscored by our expertise in cellular biology and commitment to advancing research initiatives.
Please note that all services are for research use only. Not intended for any clinical use.
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