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FCHO2 Knockout Cell Lines

Gene: FCHO2

Official Full Name: FCH and mu domain containing endocytic adaptor 2provided by HGNC

Gene Summary: Enables identical protein binding activity. Involved in clathrin coat assembly and clathrin-dependent endocytosis. Located in clathrin-coated pit and clathrin-coated vesicle. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO30615 FCHO2 Knockout cell line (HeLa) Human FCHO2 1:3~1:6 Negative Online Inquiry
KO30616 FCHO2 Knockout cell line (HCT 116) Human FCHO2 1:2~1:4 Negative Online Inquiry
KO30617 FCHO2 Knockout cell line (HEK293) Human FCHO2 1:3~1:6 Negative Online Inquiry
KO30618 FCHO2 Knockout cell line (A549) Human FCHO2 1:3~1:4 Negative Online Inquiry

Background

FCHO2 Gene Knockout Cell Lines are a specialized tool used in molecular biology to investigate the role and function of the FCHO2 gene, a critical player in the endocytic processes involved in cellular transport and signaling. These cell lines are engineered to lack functional FCHO2 gene expression, providing a unique platform for exploring gene function, cellular mechanics, and disease pathology without the interference of the gene's normally expressed products.

The primary function of FCHO2 is in clathrin-mediated endocytosis, where it facilitates the formation of clathrin-coated pits necessary for the internalization of membrane receptors and other molecules. The knockout of this gene not only aids researchers in elucidating the specific pathways influenced by FCHO2 but also allows for the study of compensatory mechanisms that may arise from its absence. This helps in understanding the broader implications of gene interactions within cell biology.

The scientific importance of FCHO2 Gene Knockout Cell Lines extends to both research and clinical settings, where they can be utilized to investigate various diseases, including cancer and metabolic disorders, that arise from dysfunctional endocytosis. Furthermore, these cell lines offer insights into potential therapeutic targets by revealing how modulation of the FCHO2 pathway could affect cellular processes.

One of the key advantages of our FCHO2 Gene Knockout Cell Lines is the precision and reproducibility they provide, enabling consistent results across experiments. Compared to other genetic manipulation techniques, such as CRISPR not specifically targeted, the knockout approach minimizes off-target effects and delivers a clearer understanding of the FCHO2 gene's specific roles, thereby allowing for more focused studies.

For researchers and clinicians, these cell lines represent an invaluable resource for dissecting complex cellular mechanisms and developing novel therapeutic strategies. By making FCHO2 knockout lines part of their toolkit, users will be able to advance their understanding of cellular dynamics and contribute to innovative biomedical breakthroughs.

Our company's expertise in developing biological products has led to the creation of these highly specialized cell lines, reflecting our commitment to supporting cutting-edge research in molecular biology. With a focus on quality and precision, our FCHO2 Gene Knockout Cell Lines are designed to meet the highest standards in laboratory research, making them an essential choice for any bioscience endeavor.

Please note that all services are for research use only. Not intended for any clinical use.

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